Bacterial Superbugs Resistant to Antibiotics - A Scary Topic
http://www.bbc.com/news/uk-england-nott ... e-32117815
1,000-year-old onion and garlic eye remedy kills MRSA
Quote:
A 1,000-year-old treatment for eye infections could hold the key to killing antibiotic-resistant superbugs, experts have said.
Scientists recreated a 9th Century Anglo-Saxon remedy using onion, garlic and part of a cow's stomach.
They were "astonished" to find it almost completely wiped out methicillin-resistant staphylococcus aureus, otherwise known as MRSA.
Their findings will be presented at a national microbiology conference.
The remedy was found in Bald's Leechbook - an old English manuscript containing instructions on various treatments held in the British Library.
Anglo-Saxon expert Dr Christina Lee, from the University of Nottingham, translated the recipe for an "eye salve", which includes garlic, onion or leeks, wine and cow bile.
Experts from the university's microbiology team recreated the remedy and then tested it on large cultures of MRSA.
Analysis
Tom Feilden, science editor Today Programme
The leechbook is one of the earliest examples of what might loosely be called a medical textbook
It seems Anglo-Saxon physicians may actually have practised something pretty close to the modern scientific method, with its emphasis on observation and experimentation.
Bald's Leechbook could hold some important lessons for our modern day battle with anti-microbial resistance.
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In each case, they tested the individual ingredients against the bacteria, as well as the remedy and a control solution.
They found the remedy killed up to 90% of MRSA bacteria and believe it is the effect of the recipe rather than one single ingredient.
Dr Freya Harrison said the team thought the eye salve might show a "small amount of antibiotic activity".
"But we were absolutely blown away by just how effective the combination of ingredients was," she said.
Dr Lee said there are many similar medieval books with treatments for what appear to be bacterial infections.
She said this could suggest people were carrying out detailed scientific studies centuries before bacteria were discovered.
The team's findings will be presented at the Annual Conference of the Society for General Microbiology, in Birmingham.
Equal amounts of garlic and another allium (onion or leek), finely chopped and crushed in a mortar for two minutes.
Add 25ml (0.87 fl oz) of English wine - taken from a historic vineyard near Glastonbury.
Dissolve bovine salts in distilled water, add and then keep chilled for nine days at 4C.
Scientists recreated a 9th Century Anglo-Saxon remedy using onion, garlic and part of a cow's stomach.
They were "astonished" to find it almost completely wiped out methicillin-resistant staphylococcus aureus, otherwise known as MRSA.
Their findings will be presented at a national microbiology conference.
The remedy was found in Bald's Leechbook - an old English manuscript containing instructions on various treatments held in the British Library.
Anglo-Saxon expert Dr Christina Lee, from the University of Nottingham, translated the recipe for an "eye salve", which includes garlic, onion or leeks, wine and cow bile.
Experts from the university's microbiology team recreated the remedy and then tested it on large cultures of MRSA.
Analysis
Tom Feilden, science editor Today Programme
The leechbook is one of the earliest examples of what might loosely be called a medical textbook
It seems Anglo-Saxon physicians may actually have practised something pretty close to the modern scientific method, with its emphasis on observation and experimentation.
Bald's Leechbook could hold some important lessons for our modern day battle with anti-microbial resistance.
line break
In each case, they tested the individual ingredients against the bacteria, as well as the remedy and a control solution.
They found the remedy killed up to 90% of MRSA bacteria and believe it is the effect of the recipe rather than one single ingredient.
Dr Freya Harrison said the team thought the eye salve might show a "small amount of antibiotic activity".
"But we were absolutely blown away by just how effective the combination of ingredients was," she said.
Dr Lee said there are many similar medieval books with treatments for what appear to be bacterial infections.
She said this could suggest people were carrying out detailed scientific studies centuries before bacteria were discovered.
The team's findings will be presented at the Annual Conference of the Society for General Microbiology, in Birmingham.
Equal amounts of garlic and another allium (onion or leek), finely chopped and crushed in a mortar for two minutes.
Add 25ml (0.87 fl oz) of English wine - taken from a historic vineyard near Glastonbury.
Dissolve bovine salts in distilled water, add and then keep chilled for nine days at 4C.
Unforunately you cannot patent this recipe so western medicine won't be talking about it. A perfectly good treatment for MRSA.
auntblabby
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http://cid.oxfordjournals.org/content/53/10/994.full
Systematic Review of Intestinal Microbiota Transplantation (Fecal Bacteriotherapy or Fecal Microbiota Transplant/FMT) for Recurrent Clostridium difficile Infection
Quote:
Clostridium difficile infection (CDI) is a gastrointestinal disease believed to be causally related to perturbations to the intestinal microbiota. When standard treatment has failed, intestinal microbiota transplantation (IMT) is an alternative therapy for patients with CDI. IMT involves infusing intestinal microorganisms (in a suspension of healthy donor stool) into the intestine of a sick patient to restore the microbiota. However, protocols and reported efficacy for IMT vary. We conducted a systematic literature review of IMT treatment for recurrent CDI and pseudomembranous colitis. In 317 patients treated across 27 case series and reports, IMT was highly effective, showing disease resolution in 92% of cases. Effectiveness varied by route of instillation, relationship to stool donor, volume of IMT given, and treatment before infusion. Death and adverse events were uncommon. These findings can guide physicians interested in implementing the procedure until better designed studies are conducted to confirm best practices.
Not quite sure why western medical doctors caught onto this, since you can't patent it either. It's approved as a treatment in Canada for C.diff but not for other chronic digestive problems even though patients could clearly benefit from having FMT I bet. Too bad nobody dies from IBS, so I guess they just don't care.