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AspergerThinker
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25 Jul 2013, 4:12 pm

I am trying, without success, to find out the exact genetic code that is found in the genes related to autism. Could anyone help me find out what it is. Your help would be appreciated.



Willard
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25 Jul 2013, 5:48 pm

My understanding is that specific genetic marker(s) have yet to be identified. I have read that current assumption is that there will be more than one.



NewDawn
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25 Jul 2013, 6:58 pm

I'm not sure what you're trying to ask.

You mean the basepair sequences of genes that are possibly related to autism ? You can find those in various genome databases such as GenBank and EMBL.

http://www.ncbi.nlm.nih.gov/nucleotide/

http://www.ebi.ac.uk/



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25 Jul 2013, 11:05 pm

There is no single "autism gene", nor does there seem to be a single copy error that can be said to be the cause (not like, say, trisomy 21 leading to Downs Syndrome). Instead, there seem to be a lot of single-gene copy errors that can contribute; further, some possible epigenetic causes have been identified (for instance, is the higher rate of autism in areas of greater air pollution due to the effects of air pollution on developing fetuses, or is it an artifact of the fact that said areas also tend toward higher-tech employment, which tends to attract people on the spectrum, or could it be some combination of these, or even just a statistical fluke?).

If you'd like to start a career in genetics with a specialty of isolating autism causes, this would seem to be a field with lots of job security...


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AspergerThinker
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26 Jul 2013, 4:50 am

NewDawn, you websites where very helpful, thank you and base pair sequences was what I meant but I forgot what they were called. Willard, people have found genes that they believe relate to autism very recently. A Google search of "genetic sequence for autism" will explain about a recent experiment. DeaconBlues, I agree that a career in genetics specializing in autism would be safe job, but I prefer the other sciences and I just wanted to find out from personal interest.



ruveyn
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26 Jul 2013, 12:57 pm

AspergerThinker wrote:
I am trying, without success, to find out the exact genetic code that is found in the genes related to autism. Could anyone help me find out what it is. Your help would be appreciated.


This is not yet known even by people doing advanced research on the matter.

No one knows whether autism is purely an inherited condition or is a condition that is also triggered by environmental factors.

ruveyn



klausnrooster
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12 Jan 2014, 1:18 am

AspergerThinker wrote:
I am trying, without success, to find out the exact genetic code that is found in the genes related to autism. Could anyone help me find out what it is. Your help would be appreciated.

http://www.bio-itworld.com/2013/10/3/gene-deletions-may-be-implicated-autism.html
Genes involved in autophagy, like trimming connections in the brain. They may be on to something.



ruveyn
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12 Jan 2014, 12:36 pm

klausnrooster wrote:
AspergerThinker wrote:
I am trying, without success, to find out the exact genetic code that is found in the genes related to autism. Could anyone help me find out what it is. Your help would be appreciated.

http://www.bio-itworld.com/2013/10/3/gene-deletions-may-be-implicated-autism.html
Genes involved in autophagy, like trimming connections in the brain. They may be on to something.


That remains to be seen.



klausnrooster
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12 Jan 2014, 5:13 pm

Yes. Listen to the man people. Correlation is not causation, and a small sample size is just that. The pharma advertising machine would like us to forget that. So would all kinds of pop-science websites.



Inventor
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19 Jan 2014, 5:39 am

It is like the genetics of any small group, patterns can be found.

Worse, is when funding is available, then patterns will be found.

The last I heard some 13 to 31 sites showed promise of more funding.

Nothing has been nailed down to all autistics have this.

In fact, it was unnailed in identical twin studies, where one was autistic.

365 days a year, yet in a class of 30, two are highly likely to share the same birthday.

The Scientific Method, isolates one thing.

Actual science does not work that way. How much funding, and what results do you seek?

Science is a Profession like Law, funding is directed to results.

When Science can find nothing, or a lawyer loses a case, they try for another round of funding, for an appeal.

We are on to something! Means we did not find anything.

I am just as close on my Fusion powered Time Machine.



eric76
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20 Jan 2014, 6:34 am

DeaconBlues wrote:
There is no single "autism gene", nor does there seem to be a single copy error that can be said to be the cause (not like, say, trisomy 21 leading to Downs Syndrome). Instead, there seem to be a lot of single-gene copy errors that can contribute; further, some possible epigenetic causes have been identified


What DeaconBlues said.



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02 Feb 2014, 8:09 pm

I am not saying it has all the answers, but lately I've been looking at a neurochemical called Reelin and the genes which regulate this.
There has been some confusion in the past about schizophrenia and autism, and I think how Reelin is regulated in the brain may have something to do with this.



TheCrookedFingers
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08 Feb 2014, 4:37 am

DeaconBlues wrote:
There is no single "autism gene", nor does there seem to be a single copy error that can be said to be the cause (not like, say, trisomy 21 leading to Downs Syndrome). Instead, there seem to be a lot of single-gene copy errors that can contribute; further, some possible epigenetic causes have been identified (for instance, is the higher rate of autism in areas of greater air pollution due to the effects of air pollution on developing fetuses, or is it an artifact of the fact that said areas also tend toward higher-tech employment, which tends to attract people on the spectrum, or could it be some combination of these, or even just a statistical fluke?).


This.
What would you do with the sequence of said numerous genes, if you found it?



Feralucce
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08 Feb 2014, 12:07 pm

AspergerThinker wrote:
I am trying, without success, to find out the exact genetic code that is found in the genes related to autism. Could anyone help me find out what it is. Your help would be appreciated.


Since these have not been isolated with any level of certainty, it is not possible to give you the information you seek


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