There is a difference between 'edible' and 'swallowable' . . .
Battery-powered, swallowable cameras the size of a large pill have been on the market since 2001. About a dozen companies make such capsules to take pictures of the esophagus, small intestine, and colon as the capsules move through the gastrointestinal tract -- offering a less invasive alternative to endoscopies and colonoscopies. And in 2012, the U.S. Food & Drug Administration cleared for human use a silicon chip the size of a grain of sand that can be embedded in pharmaceutical pills to monitor whether people are taking prescribed drugs as they should.
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Ingestible sensors would give doctors direct, real-time access to the complex chemistry present in the GI tract while it operates normally with food and liquid in it, something not currently possible via standard tests like stool studies or endoscopies. Such sensors could probe the gut’s proteins, electrolytes, enzymes, hormones, and metabolites -- plus the trillions of bacterial cells that influence many aspects of human health. In the stomach, imbalances in the levels of gastric acids, digestive enzymes, hormones, and more can indicate disorders, such as ulcers, inflammation, or cancer. Short-chain fatty acids in the colon are a signature of its health. The small intestine carries a similar complex mixture. Makers of ingestible sensors want to dig into this trove of information.
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