Not sure if I said before, but The Magic School Bus would be awesome as live-action.
Idea: It's many years later. The kids are now grown-up and living well away from each other, especially Carlos and Dorothy Ann. All receive a mysterious e-mail from someone claiming to be Ms. Frizzle, their old teacher. Ms. Frizzle, now hiding well into retirement claims she has opened the portal to an alternate reality where she is still teaching. Everyone is skeptical, the most being Arnold, now a geologist with expertise in urban planning. When they meet for the first time, they meet younger versions of Ms. Frizzle who refuse to give up the whereabouts of the "real" Ms. Frizzle. Both Ms. Frizzles take the group on...A FIELD TRIP.
Ms. Frizzle: Lily Tomlin
Young Ms. Frizzles: Cate Blanchett and Tilda Swinton
Arnold: Jon Heder
Carlos: "a relative unknown"
Keesha: "a relative unknown"
Phoebe: Amy Adams
Hey wait a minute...
A movie will be made after all, with Amy Adams as Ms. Frizzle.
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Silly NTs, I have Aspergers, and having Aspergers is gr-r-reat!