One of those shows that i sometimes find funny, but don't consider amazingly groundbreaking or anything, but definitely watchable if there isn't much else to do wih my time...
Malcolm definitely has AS traits and Reece and Dewey definitely both have traits of ADD, Dewey maybe AS as well... Malcolm perhaps seems a bit too "socially smart" to be actually diagnosed As tho...
(they're all fictional characters anyway, so ultimately they don't have to conform to any "real world" psychological categories, since they're whatever the author rather than nature wants them to be... but i find "diagnosing" fictional characters to be amusing...
)
Stevie's also a positive disabled character (whose disability is rarely remarked on), as well as breaking standard racial stereotypes, so i think (for mainstream American TV at any rate) MitM's kind of cool...