That's a real hot-button word for most Aspies, I think. I'm an adult and don't react to it at all well, so I can understand kids going crazy over it. Strangely, I'm dealing with it a little bit now for the first time in ages. I've started studying with a new drum teacher, and he calls my left hand "ret*d." Not me, per se -- just my left hand because it's slower and weaker than my right. All in all, it's true and he's technically correct in a way. Still cringe every time he says it though...
To answer your direct question, I would tend to implode (rather than explode) at being called that.
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Put the curse of loneliness on every boy and every girl,
Until everybody's kickin', everybody's scratchin',
Everything seems to fail ?
And it was all for the want of a nail.