At my old job my boss went through that. She knew I had Asperger's, and was all nice to me in the first year. Then in the second year she started taking her frustrations out on me. She even yelled at me for something I didn't do, and when I tried telling her it wasn't me, she argued that it was and made me feel like a liar. Then she kept putting me on tasks she knew I didn't like, and kept accusing me of not doing my work properly. I really don't know why she started being like that towards me, but I talked to the management about it and they had a little meeting with her. To this day I'll never know what was said, but after that she started being nice to me again.
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Female