My 14 year old daughter has aspergers and she really likes orange oil, not sure if it calms her down, but she likes it and I should offer it to her more often. I like natural remedies too and have her on melatonin for sleep for the past year (1 mg about 90 minutes before bed) and I started her on 100 mg a day of 5HTP since July and it has really helped her anxiety. I am not sure if it helps her focus (she has some ADHD hyperactivity) because she is now in an aspergers program in high school. Her teacher has told me she is a pleasure to have around and her last teacher for two years did not feel this often. My daughter doesn't have any side effects from any of these remedies, just better sleep and a lot less anxiety.