IgG ELISA Tests
Tyri0n
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I had one done and it found 0 significant IgG except for baker's yeast, which was a "3." Everything else was "1" or lower. Gluten and casein were both "1" which is supposedly "insignificant" according to my doctor. Most things checked in at 0. A separate test for celiac disease (which is unrelated to IgG) came up negative as well.
I did a search for this test, and it has been criticized as giving false positives for food allergies. But could it also give false negatives?
I strongly suspect I do not have any food allergies or intolerance except maybe yeast, so I will avoid baked goods, which I don't eat much anyway. I do lower GI pain after eating certain foods, but the doctor suggested candida or bad bacteria balance instead of food intolerance.
Also, the doctor, who is used to dealing with autistic children, said "if you had autism before, you've clearly grown out of it. Maybe you grew out of food allergies and grew out of autism along with it."
I don't know whether this was just ignorant or insightful since this doctor does deal extensively with GI issues and food allergies in autistic children.
Kjas
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Unfortunately a lot of these tests are not 100%.
I know that the test for celiac disease has a false negative rate of 30% with blood tests and with biopsies. It's higher if you haven't been eating the set amount of gluten every day for the last 6 months which is needed to make the test accurate.
As for allergies, intolerances and others: it entirely depends on if they are testing IgA, IgG or IgE. Some will only test one. Some will test all three. Some will do it by hair samples, others will do it by blood samples. It's currently unknown whether you need to be a certain amount of the food daily for a set amount of time to even know if the tests will be accurate (so far it appears you don't for allergies, but you do for intolerances or autoimmune related reactions that aren't allergies). But yes it is possible to have false negatives which I hear are fairly frequent, and occasionally, false positives with them.
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Tyri0n
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Joined: 24 Nov 2012
Age: 38
Gender: Male
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Location: Douchebag Capital of the World (aka Washington D.C.)
I know that the test for celiac disease has a false negative rate of 30% with blood tests and with biopsies. It's higher if you haven't been eating the set amount of gluten every day for the last 6 months which is needed to make the test accurate.
As for allergies, intolerances and others: it entirely depends on if they are testing IgA, IgG or IgE. Some will only test one. Some will test all three. Some will do it by hair samples, others will do it by blood samples. It's currently unknown whether you need to be a certain amount of the food daily for a set amount of time to even know if the tests will be accurate (so far it appears you don't for allergies, but you do for intolerances or autoimmune related reactions that aren't allergies). But yes it is possible to have false negatives which I hear are fairly frequent, and occasionally, false positives with them.
They tested for IgG.
Is it common to have intolerances to almost nothing (except for yeast) but to have many of them wrong? I am just trying to rule out allergies as a cause of my ASD since there was a strong correlation in my early childhood of food allergies and onset of symptoms.
They tested 250 foods, and I came out as intolerant to precisely 1 of them.
Kjas
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Joined: 26 Feb 2012
Age: 35
Gender: Female
Posts: 6,059
Location: the place I'm from doesn't exist anymore
Is it common to have intolerances to almost nothing (except for yeast) but to have many of them wrong? I am just trying to rule out allergies as a cause of my ASD since there was a strong correlation in my early childhood of food allergies and onset of symptoms.
They tested 250 foods, and I came out as intolerant to precisely 1 of them.
And without testing for the other 2, you're very unlikely to get the whole picture.
For instance, mine showed issued from IgA with gluten and casein.
With IgE it only showed potato (which causes pretty bad reactions).
And with IgG showed gluten, soy and dairy.
All up that's quite a lot but if I had only had one I would have missed anywhere from 3-4 and only got 1-2 figured out.
And like the poster above pointed out, many of those things are in food and you don't realize it, especially processed food.
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Tyri0n
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Joined: 24 Nov 2012
Age: 38
Gender: Male
Posts: 2,879
Location: Douchebag Capital of the World (aka Washington D.C.)
Is it common to have intolerances to almost nothing (except for yeast) but to have many of them wrong? I am just trying to rule out allergies as a cause of my ASD since there was a strong correlation in my early childhood of food allergies and onset of symptoms.
They tested 250 foods, and I came out as intolerant to precisely 1 of them.
And without testing for the other 2, you're very unlikely to get the whole picture.
For instance, mine showed issued from IgA with gluten and casein.
With IgE it only showed potato (which causes pretty bad reactions).
And with IgG showed gluten, soy and dairy.
All up that's quite a lot but if I had only had one I would have missed anywhere from 3-4 and only got 1-2 figured out.
And like the poster above pointed out, many of those things are in food and you don't realize it, especially processed food.
Well, there was another test only for gluten, soy, dairy, and meats that, I think, tested IgA which was negative also.
As for yeast, it was only baker's yeast. Brewer's yeast came out normal. So only baked goods are the problem?
By the way, I think some of the foods that show +1 are a problem, like coffee. Maybe I should just take +1 as indicative of intolerance rather than +2 and above like the doctor recommended? The +1's seem to track gluten, casein, and salicylates fairly closely.
I don't think gluten is an issue by the way, nor do I think casein causes problems. So far, I have only identified 9 things that seem to cause gut inflammation:
1. certain hot peppers / bell peppers
2. coffee
3. msg
4. certain artificial flavors/seasoning mixes
5. sugar
6. Ginseng
7. baked goods (but not beer, so probably baking yeast rather than gluten)
8, vinegar
9. soy sauce but not soy milk -- so maybe salt as well?
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