The Halo series started with new styles of Achievements in the second game in order to combat this very phenomenon. For instance, there are achievements for simply completing the game mode in Reach on every level except Easy (Normal: The Soldier We Need You To Be, Heroic: Folks Need Heroes, Legendary: Gods Must Be Strong); achievements for accomplishing certain goals in Matchmaking (30 kills in a single game: Like Mike, killing an enemy with grenades: More Than a Handful, getting the first kill in a match: Yes, Sensei); achievements for doing some odd things in the Campaign (kill 7 Moas (flightless birds raised for meat on Reach): KEEP IT CLEAN, go through the 2nd mission without using a vehicle: They've Always Been Faster, complete the 9th mission with the Scorpion tank intact: Tank Beats Everything! [itself a quote from Halo 3]), etc.
Achievements in Mass Effect are awarded for things like completing the majority of the storyline with a given character in your party, taking out a certain number of enemies with a particular weapon, your first landing on an "uncharted" world, using a given biotic power a certain number of times, completing the storyline a second time, reaching certain levels, and so forth.
One in Grand Theft Auto IV that I don't think I'll ever get requires that when you complete the game, all the NPCs still alive like you at a level of 90% or higher. Part of the secret is to accept any invitations to hang out that you get, then call back the ones you didn't want to accept and excuse yourself (that doesn't work as well on Dwayne, if you side with him against Playboy X - after a while, Dwayne starts to take it personally; then again, he is clinically depressed).
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Sodium is a metal that reacts explosively when exposed to water. Chlorine is a gas that'll kill you dead in moments. Together they make my fries taste good.