Yes.
I usually only get it with older first person shooters (I first noticed it back in the day with Wolfenstein 3D), but it varies...I guess it depends on how long it's been since I've played them. Sometimes I can go back as far as the first two DOOMs and be perfectly fine for hours, sometimes it will have been so long that even Quake will trigger it.
I've also had it happen with Sonic Adventure 2 on the Dreamcast, but been perfectly fine with the first Sonic Adventure. I wonder if it has something to do with 2 being 60 FPS vs. 1 at 30 FPS.
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I'll brave the storm to come, for it surely looks like rain...