Well I went to a midnight release and got it now. Can't say the midnight release was all that...
Anyway, the game seems pretty nice so far. These are my comments so far.
First big noticeable thing I'd say it the revamped physics. The physics are a lot more realistic than in the PS2 games. Can be a good or bad thing depending on the player. It just something that will take getting used to. It also makes for some nifty crashes.
Police and even pedestrians are much more aggressive. Most peds aren't going to be afraid to take you on if you piss them off. (I pick a fight with one dude and strangely enough, two other peds come up start attacking me also) Police are a bit more picky now, but with the new system of getting out of their range, or resisting arrest, it feels fair.
Drivers will hit you if you block traffic.
Can't stand on cars and let them drive you around anymore. (Do this on a police car and they will try to bust you)
Dialog can sometimes change if re-doing a mission.
Haven't done much with the gunfighting yet, only one mission so can't really say much about it right now.
You can call the police/paramedics/fire dept. I've gotten police to bust aggressive peds. Supposedly the paramedics will heal you but I haven't actually figured out to get them to do it though.
Doesn't seem to be any random pickups around anymore. Heath, guns, armor... I guess you have to get those things through contacts now.
Edit: Oh, and one more thing... It's really suggested you play this on something with HD. I initially used it on my friends TV which did 1080i, but even with that it was quite hard to read the messages on the cell phone. I can play it in 720p at home which hopefully will be much better.
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