I can't think of a reason that AS precludes a person from aspirations of a religious nature. In fact if a person is a Catholic I would think that AS would lead a person to be a very good nun or monk. Same would be true of Buddhism. Unless, of course, that person were Theravada, because I think that someone with AS might have trouble with going up to people and begging for rice. If someone does not believe that religion can be intellectual that person should read some of the writings of Thomas Aquinas or maybe one of the Reformers like Martin Luther or John Wyclyff (although anybody who studies Luther would probably agree that Luther doesn't appear to be much of a mental giant, just an everyman who came across a good idea and was able to put it into words). And Buddhism doesn't need to be Zen: try reading the Lotus Sutra, or even the Diamond Sutra. The Diamond Sutra is one of the bases of Tibettan Buddhism, for all you Dali Lama fans.
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My life is a dark room. One big dark room.
-Lydia Dietz, "Beetle Juice"