cyberdad wrote:
The thinking behind this treatment is understandable if a little uncomfortable.
There's a number of "funded" projects around the world looking at the link between gut bacteria and neurological changes in the brain. There is a theory that children genetically predisposed to autism who take antibiotics as babies lose a lot of their normal flora which is disproportionately replaced by antibiotic resistance bugs in their gut. These new bacteria produce chemicals which interfere with brain function during crucial developmental stages resulting in autistic brain function (so the theory goes).
Therefore the stool treatment envisages that stool from a "healthy" person without autism contains normal flora which when consumed will reinoculate the gut replacing the bad bacteria and reducing the production of these brain altering chemicals.
Yes. I think it is the fecal part which is triggering disgust (understandably). This isn't something to be done at home (just as no parent should ever undertake to give their kid a tonsilectomy at home). It is going out on a limb to apply it to autism. But it is a limb that warrants research. It's not ridiculous.
It's already succesfully in use to treat
C. diificile infection and is being trialed for other intestinal dysfunction. The autism angle is not yet being considered in hospitals but may eventually be if ongoing research justifies trialing it and probably also if it turns out to help gut conditions beyond
C. difficile infection.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742951/Quote:
Fecal microbiota transplantation (FMT) has attracted great interest in recent years, largely due to the global Clostridium difficile infection (CDI) epidemic and major advances in metagenomic sequencing of the gastrointestinal (GI) microbiota, with growing understanding of its structure and function. FMT is now recommended as the most effective therapy for relapsing CDI and, with further refinement, may even be used in “first-time” CDI. There is interest also in other conditions related to GI dysbiosis—for example, inflammatory bowel disease, irritable bowel syndrome, obesity, and diabetes mellitus—although quality evidence is at present lacking. A few trials are now underway in FMT for ulcerative colitis. Many unanswered questions remain, including FMT methodology—for example, optimal route of administration, what makes a “good donor,” safety issues, and long-term effects of FMT.
None of that is about autism. I posted it to show that fecal transplant is not equivalent to 'bleach therapy' or any of the other dangerous practices quacks promote. This is legit although not (yet?) applied to autism in hospitals.