Emergence of a Deadly Coronavirus

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^^ That's wonderful news jimmy.

I'm not sure if I read it properly. Will this drug potentially help patients who are immunocompromised by breast cancer if they also contract COVID-19, or is it two separate uses? I worry a lot about people who are susceptible to this virus because of their cancer treatment.

South Dakota Gov. Kristi Noem on Monday announced a statewide clinical trial of hydroxychloroquine for the possible treatment of COVID-19, making her state the first in the country to institute a program exploring the potential effectiveness of the drug in treating and preventing coronavirus.

“Today, I’m pleased to report we have received the initial doses we need, and thanks to the leadership of Sanford Health and the assistance of medical teams at Avera and Monument Health, we’re going to be the first state in the nation to do a comprehensive clinical trial to assess whether hydroxychloroquine can treat and perhaps even prevent COVID-19,” she said.

Sanford Health is the largest provider of rural health care in the country, according to Noem. With the help of Avera and Monument Health, they will treat “up to 100,000 people including outpatient and hospitalized patients with COVID-19, in addition to frontline health care workers, and high-risk individuals who have been exposed to the virus.”

Source: South Dakota implements statewide hydroxychloroquine clinical trial for potential coronavirus treatment

More than 100 South Koreans who fully recovered from coronavirus have tested positive for a second time. The killer virus has “reactivated” in a total 116 patients, with 48 of them in the nation’s coronavirus epicenter of Daegu, according to Yonhap News Agency. Jeong Eun-kyeong, director of the Korea Centers for Disease Control and Prevention, said the virus may have been reactivated after remaining dormant in the patients, as opposed to them being reinfected. The country reported last week there were 51 cases of patients testing positive after being cleared of the virus. Jeong noted, however, there have been no cases of the relapsed patients spreading the virus to anyone else, Yonhap News reported.

Source: Coronavirus has 'reactivated' in more than 100 South Koreans who recovered

This sort of reminds me of the relationship between chicken pox and shingles. Shingles is caused by the varicella-zoster virus — the same virus that causes chickenpox. After you've had chickenpox, the virus lies inactive in nerve tissue near your spinal cord and brain. Years later, the virus may reactivate as shingles.

^ wonderful

That’s what worries me.
Viruses going dormant and then popping back up.
Herpes is one.

I think it will take a combination of AI and “outside the box” human thought to come up with the correct combination of compounds to find a “cure” for this virus. Even then, it will take time to test it and then mass produce it for the world. I do not want to get into the technical issues over who “owns” the drug rights, as that is another nightmare for another time.

One thought that I did have a while ago is that we might be able to use genetically modified bacterial to mass produce target compounds once they have been identified. The bacteria act as a catalyst in the reaction process. That is a crapshoot, but it is a possible tool to use. Some of the target drugs likely contain chiral carbon centers, leading to racemixation of isomer products if the synthesis is done in a laboratory beaker. The problem is one of the isomers might work, while the other does not. If you use the mixed forms in a drug without separating them, it will likely not be effective and/or it will likely have side effects worse than the virus infection. Biological reactions can be done that only form the particular isomer needed, but one has to know the biochemistry of the biological used in and out. Any slight miscalculation will lead to failure.

Don't you wish you could go back in tame and slap a bat out of someone's hands?

Yeah ,but they’d just start rummaging around and shake another out of a tree.

I’m not saying that the 116 reinfections is great. But it should be pointed out that 7,447 people have recovered in South Korea, per Worldometer.

We have to get to the bottom of why reinfections occurred.

The drug companies can even spread it by accident:

https://news.yahoo.com/premier-u-drug-c ... 42563.html

New York Man slashes tires on 22 vehicles of nurses working overnight shift
https://www.yahoo.com/huffpost/daniel-h ... 33888.html

"29-year-old Daniel R. Hall of Peekskill and charged him with criminal mischief and auto stripping".

"Just hours earlier, dozens of police officers and firefighters gathered outside the hospital to applaud health care workers"

Peekskill is about 20 miles north of the northernmost part of NYC, and about 35 or so miles from my part of Queens.

I hope they charge this person with a felony.