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jimmy m
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04 Feb 2021, 9:10 am

Natural Immunity

Exposure to the disease organism can occur through infection with the actual disease resulting in natural immunity.

The research from UK Biobank found that 99 percent of participants who had tested positive for previous infection retained antibodies for three months after being infected, while 88 percent did so for the full six months of the study, according to Sky News.

"This important study has revealed that the vast majority of people retain detectable antibodies for at least six months after infection with the coronavirus," said Professor Naomi Allen, UK Biobank chief scientist."Although we cannot be certain how this relates to immunity, the results suggest that people may be protected against subsequent infection for at least six months following natural infection," Allen said.

"More prolonged follow-up will allow us to determine how long such protection is likely to last," she added.

Source: Adults age 20 to 49 are biggest COVID-19 spreaders in US, study says


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04 Feb 2021, 9:12 am

I've been taking the subways in NYC for six months now. I've tested negative about 15 times in those six months.

I had COVID in late March, and tested positive for antibodies in late May.



jimmy m
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04 Feb 2021, 9:44 am

Getting Vaccinated

Back in October, 58% of the U.S. Public said they would get the COVID vaccine as soon as it was available. The media and the anti-vaxxer movement had a major impact on the perception in destroying confidence in the vaccine prior to the roll-out. Some were predicting doom for the program because once it crossed the finish line, no one would want it.

My observations is that most people do not want to be the first in line when some new medicine is introduced with some potential risks and that once it became available and people received their shots, then people would see that the side effects were vastly overrated.

So now several months have passed, the vaccines have been released. And it is almost like a Black Friday sale with people rushing in line to get their shots. I had my first shot of the Moderna vaccine a couple weeks ago. Side effects were minimal. Only a bit of a sore arm for a day or two.

On Monday of this week my State of Indiana lowered the vaccine eligibility to those 65 year old and older. So we immediately signed my wife up for her appointment to get the shot. She was not the only one. On Monday nearly 103,000 people made appointments for their first vaccine dose on that day alone.


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jimmy m
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04 Feb 2021, 3:12 pm

High Tech Censorship

When this pandemic began, right at the very beginning, the World Health Organization met with many high tech companies and implemented a censorship program. They said that their goal was to remove misinformation. They claim to be the ultimate medical authority. Many of the advise given by the WHO on this pandemic turned out to be wrong. WHO and high tech colluded to use their platforms to stifle any alternative view. Why didn't they censor the Anti-Vaxxer? Instead they censored doctors and other medical professionals and silenced them.

Dr. Kory testified before the Committee on Homeland Security and Governmental Affairs in December, citing the use of a widely available drug called ivermectin, as a potential early treatment and prevention of COVID-19. The drug, which is widely available to treat tropical diseases caused by parasites, showed promising results from a study done in Argentina. In the study, 800 healthcare workers received ivermectin, while another 400 did not. Of the 800, not a single person contracted COVID-19, while more than half of the 400 did.

On 27 January, YouTube censors removed Dr. Kory presentation from the Internet.

Louis Brandeis, Supreme Court justice had a decision almost 100 years ago in 1927 that actually dealt with falsehoods and fallacies that might cause societal harm said ‘the remedy to be applied is more speech, not enforced silence.’ That was pretty wise back then, but we’re moving in the exact opposite direction now.

Source: 'Dangerous' for YouTube to remove doctor's Senate testimony on coronavirus treatment: Ron Johnson


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Last edited by jimmy m on 04 Feb 2021, 3:27 pm, edited 1 time in total.

jimmy m
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04 Feb 2021, 3:26 pm

Thapsigargin

A plant-derived antiviral medication may be "highly effective" in treating the coronavirus — and could also help fight future pandemics, according to new research in the UK. The scientists found that the antiviral, in small doses, triggers a "highly effective" immune response against the three major types of human respiratory viruses, including COVID-19. It is able to prevent a virus from making new copies of itself in cells for at least 48 hours after a single 30-minute exposure, according to the study.

Researchers at the University of Nottingham found that the broad spectrum antiviral thapsigargin is not only very effective against COVID-19, but also against a common cold coronavirus called respiratory syncytial virus and influenza A, Eurekalert.org reported.

Source: Plant-based antiviral drug may help beat COVID-19, research shows

"Whilst we are still at the early stages of research into this antiviral and its impact on how viruses such as COVID-19 can be treated, these findings are hugely significant," said Professor Kin-Chow Chang, who led the study along with colleagues at the Animal and Plant Health Agency, China Agricultural University and the Pirbright Institute."The current pandemic highlights the need for effective antivirals to treat active infections, as well as vaccines, to prevent the infection," he said.


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jimmy m
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04 Feb 2021, 4:52 pm

Aerosol Transmission

A team of scientist looked at the transmission mechanism [large droplet, formite and the inhalation of aerosols] for COVID-19 on the cruise ship the Diamond Princess. The model that they developed showed that aerosol transmission was the predominant mechanism for virus transmission aboard the Diamond Princess. Mean estimates of the contributions of larger respiratory droplets and smaller respiratory aerosols were 41% and 59%, respectively.

Mechanistic transmission modeling of COVID-19 on the Diamond Princess cruise ship demonstrates the importance of aerosol transmission

We will never overcome this pandemic until we recognize the effect of aerosol transmission and implement steps to limit aerosol spread.


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04 Feb 2021, 5:18 pm

jimmy m wrote:
Aerosol Transmission

A team of scientist looked at the transmission mechanism [large droplet, formite and the inhalation of aerosols] for COVID-19 on the cruise ship the Diamond Princess. The model that they developed showed that aerosol transmission was the predominant mechanism for virus transmission aboard the Diamond Princess. Mean estimates of the contributions of larger respiratory droplets and smaller respiratory aerosols were 41% and 59%, respectively.

Mechanistic transmission modeling of COVID-19 on the Diamond Princess cruise ship demonstrates the importance of aerosol transmission

We will never overcome this pandemic until we recognize the effect of aerosol transmission and implement steps to limit aerosol spread.



So there was not even a 1% of contact transmission? A 100% airborne transmission in this case? 8O



jimmy m
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04 Feb 2021, 5:35 pm

The_Face_of_Boo wrote:
jimmy m wrote:
Aerosol Transmission

A team of scientist looked at the transmission mechanism [large droplet, formite and the inhalation of aerosols] for COVID-19 on the cruise ship the Diamond Princess. The model that they developed showed that aerosol transmission was the predominant mechanism for virus transmission aboard the Diamond Princess. Mean estimates of the contributions of larger respiratory droplets and smaller respiratory aerosols were 41% and 59%, respectively.

Mechanistic transmission modeling of COVID-19 on the Diamond Princess cruise ship demonstrates the importance of aerosol transmission

We will never overcome this pandemic until we recognize the effect of aerosol transmission and implement steps to limit aerosol spread.


So there was not even a 1% of contact transmission? A 100% airborne transmission in this case? 8O


The paper read "Mean estimates of the contributions of short-range, long-range, and fomite transmission modes to infected cases across the entire simulation period were 35%, 35%, and 30%, respectively.'

So I believe the paper gave a 30% transmission rate to formite spread. The 59% related to aerosol transmission in airborne spread.


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jimmy m
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04 Feb 2021, 10:32 pm

Progress of COVID Inoculations

According to the coronavirus vaccine tracker, the U.S. has now administered 36.68 million vaccine doses with around 11% of the U.S. population vaccinated (with at least one dose). In the United States an average of 1.34 million doses were injected daily.

Globally 119.76 million vaccine doses have been given with the U.S., China and U.K. in the top three positions.

Source: COVID-19 Vaccine Tracker


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05 Feb 2021, 9:10 am

CDC director says schools can safely reopen without vaccinating teachers

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Teachers do not need to get vaccinated against Covid-19 before schools can safely reopen, the head of the Centers for Disease Control and Prevention said Wednesday.

“There is increasing data to suggest that schools can safely reopen and that safe reopening does not suggest that teachers need to be vaccinated,” CDC Director Dr. Rochelle Walensky told reporters during a White House news briefing on Covid-19.

“Vaccinations of teachers is not a prerequisite for safely reopening schools,” she added.

During a press briefing later Wednesday, White House press secretary Jen Psaki walked back Walensky’s comments, saying that they were not “official guidance” from the CDC.

A study from the CDC published late last month found little evidence of the virus spreading at schools in the U.S. and abroad when precautions were taken, such as wearing masks, social distancing and ventilating rooms.

The Biden administration has released a Covid rescue plan that includes providing schools and universities with $170 billion to reopen. The money would be used in part to scale up testing. The administration has said testing is a “critical” strategy for controlling the spread of the virus, but added tests are still not widely available, and the U.S. is still not using the ones it has effectively.

Walensky has previously said that schools should be the first to open and the last to close in the pandemic.

Jeff Zients, President Joe Biden’s Covid-19 czar, said Wednesday that Biden has been “very clear” that he wants schools to “reopen and to stay open.”


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Last edited by ASPartOfMe on 05 Feb 2021, 10:52 am, edited 1 time in total.

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05 Feb 2021, 9:30 am

Jakki wrote:
Seen this too .. TY for info.. sorry but could not resist being punny with this: Simple answer ?
stop drinking Corona beer ? or chinese fish?

... ... ...
[Burst of laughter]...Thank you, Jakki...We should never lose our good sense of humor... :D :wink: :heart:



jimmy m
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05 Feb 2021, 9:31 am

Most of Indiana schools reopened in August of last year. There is a requirement for social distancing and mask wearing. In some of the younger grades, children are segregated into pods. They go to the same classroom, eat lunch together. Pods can be quickly quarantined if one member tests positive. Most schools take a flexible approach. If infection rates go up, they selectively begin to punt towards a variety of hybrids (distant learning, reduce the days of in-class school and use distance learning for the other days, total closure for a week or two). Everything seems to work smoothly.


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07 Feb 2021, 4:16 pm

Experts predict young children won't get COVID-19 vaccines until 2022
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Most children probably won’t be able to receive COVID-19 vaccines until 2022, as research on them lags months behind studies on adults, experts say.

Pediatricians disagree on whether vaccine clinical trials involving children should have begun earlier. But they concur that vaccinations of kids would help protect both them and adults in their household, hasten the arrival of herd immunity — when the virus' ability to spread is greatly limited — and return kids to a more normal childhood.

"Vaccination is a really important tool in our tool kit for allowing kids to fully get back to all of those things that are really important to their health and development," said Dr. Lee Savio Beers, president of the American Academy of Pediatrics, citing the social isolation and academic disruptions the pandemic has caused.

The U.S. Food and Drug Administration authorized adolescents as young as 16 to receive the Pfizer-BioNTech vaccine, because there was enough data from clinical trials on them. But Pfizer did not finish enrolling 12- to 15-year-olds in trials until last month. The company will begin studying children 5 to 11 "when we have data for the 12- to 15-year-old cohort," company spokeswoman Keanna Ghazvini said in an email.

That means kids 12 to 15 wouldn’t be able to start receiving the vaccine until the summer at the earliest, and that younger children likely wouldn’t be authorized to get it until early 2022, said Dr. Sharon Nachman, chief of pediatric infectious diseases at Stony Brook Medicine and one of six members of the state's clinical advisory task force, which reviews vaccines.

Only those 18 and older can currently take the vaccine from Moderna, manufacturer of the only other FDA-authorized vaccine. The company is still enrolling kids 12 to 17 in clinical trials, according to a federal clinical-trial website.

Vaccine-makers AstraZeneca and Johnson & Johnson are expected to begin clinical trials involving older children in the next few months.

Nachman, who in September co-authored a paper in the journal Clinical Infectious Diseases calling for the inclusion of children in clinical trials, said that, for months, there has been enough safety data for the two authorized vaccines on adults to go forward with studying children as young as 2.

Pfizer and Moderna are following the traditional path of first studying older kids and waiting to study younger ones, she said. But that approach must be balanced with the deaths and hospitalizations that COVID-19 has caused among children, the unknown long-term effects of the virus on kids who contract it, and children's ability to transmit the virus to vulnerable adults, she said.

"I think in the time of a pandemic such as this, with knowing the efficacy of the vaccine in adults, it should be all the age groups, 2 and over, studied at the same time," she said. "That would accelerate our ability to get an answer and vaccinate children."

Nachman said dosage for some noncoronavirus vaccines is the same for adults and children, while for others it may be different based on age. But, she said, "There is no vaccine that is efficacious in adults and not efficacious in children."

Dr. Leonard Krilov, chief of pediatrics at NYU Langone Hospital-Long Island in Mineola and an infectious disease specialist, agreed with Nachman on the likely timetable for vaccine rollout for kids. But he said that with relatively low COVID-19 death rates for children, it is sensible "to go slowly."

"I think it’s a safety-first issue," he said. "As you get younger, you might have to address dose and side effects differently."

Young children may have different side effects because their bodies are smaller and not as immunologically developed, Krilov said.

Twenty-three of the more than 36,000 New Yorkers who have died of the disease have been under 20, according to the New York State Health Department. In addition, at least two New York children have died of multisystem inflammatory syndrome, a disease linked to COVID-19.

Beers said "we do have concern things could have moved a bit faster" with the ground work needed to prepare for clinical trials in children. But, she said, drug companies should follow the traditional route of studying kids by age group.

"Older children are physiologically more similar to adults, and so as we establish efficacy and safety in adults, then we can start to be able to better understand how the vaccine will work in children," Beers said. "We don’t expect major differences, but it’s important to establish that safety and efficacy."


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11 Feb 2021, 1:19 am

More side effects reported after 2nd dose, but experts say there’s a reason

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As the vaccination campaign against COVID-19 continues and more people receive their second dose, many have reported that it caused more intense side effects than after the first. But vaccine experts say this news is both normal and expected.

"It’s a sign that your immune system is working," said Dr. Williams Moss, an epidemiologist and executive director of the International Vaccine Access Center at Johns Hopkins.

Side effects from the vaccines being used in the U.S., developed by Moderna and Pfizer-BioNtech, are normal signs your body is building protection. The CDC says flu-like symptoms are to be expected and can include fever, chills, headache, muscle aches and tiredness. Some may have pain and swelling in the arm at the site of the injection. All side effects should go away within a few days.

Users of V-safe, the CDC’s tool to report vaccine side effects, have reported more side effects within a week of getting their second shot, compared to the first.

Mark Sussman, who recently got his second dose of the Moderna vaccine, said he felt sick for about a day and a half.

"Chills, shortness of breath, muscle ache, general just soreness," Sussman described to FOX 5 DC, days after receiving his second shot. Sussman added that it wasn’t a "full-blown flu," but side effects did stick around for about 36 hours.

But not everyone feels side effects. Sussman’s mother also recently got a second dose of the Pfizer vaccine and felt fine.

There are spike proteins on the surface of SARS-CoV-2, the virus that causes COVID-19, which are critical for the virus to bind to the body’s cells and replicate. All of the developed COVID-19 vaccines work to induce an immune response against the spike protein, primarily through antibodies.

Instead of injecting the virus, Moss explained that mRNA vaccines work by injecting a "recipe" for the spike protein, or the genetic code, causing cells to produce the spike protein.

"Through that mechanism, our own cells producing the spike protein, then what happens is our immune system will see that protein and will recognize it as foreign," triggering an immune response, he said.

This immune response is known broadly as inflammation, which can result in side effects such as redness, swelling and tenderness at the injection site. It can also mean a broader systemic response in the body, such as fever, headache, muscle ache, joint pain or fatigue.

The first dose of the vaccine primes the immune system, building an army of cells. As a result, Moss said the second dose then generates a bigger immune response — hence the possibility of stronger side effects.

"We’ve got many more cells available to attack it," Moss explained. "But that’s why the inflammation can be more severe with the second dose because our immune system is kind of already primed, so you get an even more intense inflammatory response."


NY man dies shortly after vaccination, allergic reaction not suspected
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A man died shortly after receiving a COVID-19 vaccination at the Javits Center in Manhattan but it was not believed to be due to an allergic reaction, state officials say.

The man, in his 70s, collapsed as he was leaving the vaccination site on Sunday morning.

"On-site security and first responders were by his side within seconds, but sadly the man passed away a short time later at a hospital," New York State health Commissioner Howard Zucker said in a statement to Fox5NY.com.

The incident occurred approximately 25 minutes after he was vaccinated, and following the required 15 minute observation period. Heath officials say he exhibited no adverse reactions or any distress. They added that initial indications are that the man did not have any allergic reaction to the vaccine.


Up to 50,000 COVID-19 cases can be traced back to Mardi Gras 2020, study finds
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More than one million people from all over the U.S. were drawn to Mardi Gras celebrations in New Orleans last February during the dawn of the pandemic.

Now, a new study shows the absence of COVID-19 safety regulations during that time period likely caused it to be a superspreader event that spawned up to 50,000 cases.

Researchers at the Scripps Research Institute, Tulane University, LSU Health Shreveport and other institutions said in the pre-publication study, "Emergence of an early SARS-CoV-2 epidemic in the United States," that evidence showed the Mardi Gras festival in New Orleans was likely a superspreader event.

"We show that SARS-CoV-2 was already present in New Orleans before Mardi Gras and that the festival dramatically accelerated transmission," the study authors wrote. "Although we did not attempt to estimate the exact magnitude of the Mardi Gras superspreading event ... it seems likely that the majority of the ~50,000 confirmed COVID-19 cases during the first wave can be traced back to Mardi Gras."

Researchers analyzed over 30,000 pieces of each virus and found that one successful introduction of the virus led to almost all the early COVID-19 transmission in the state.

According to the study, the virus was likely introduced into Louisiana through domestic travel two weeks before Mardi Gras, likely from a person traveling from Texas.

"Unrestricted domestic travel in the U.S. in February 2020 and associated large travel volumes likely facilitated the emergence of SARS-CoV-2 in Louisiana," the authors wrote.

"To determine whether the festival may have accelerated the early COVID-19 epidemic in Louisiana, we modeled the number of likely daily cases using reported deaths and compared these with simulated case numbers that, based on our TMRCA estimates, assumed local transmission started on February 13th, 2020. We found that the observed number of infections was substantially higher than the expected number of infections, suggesting superspreading during Mardi Gras," the authors explained.


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11 Feb 2021, 8:31 am

Egypt 5th Jan - ICU central system malfunctioned, everyone on the ICUs in this ward died.




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11 Feb 2021, 8:12 pm

Progress of COVID Inoculations

According to the coronavirus vaccine tracker, the U.S. has now administered 48.03 million vaccine doses with around 14.5% of the U.S. population vaccinated (with at least one dose). In the United States an average of 1.62 million doses were injected daily.

Globally 159.35 million vaccine doses have been given with the U.S., China and U.K. in the top three positions.

Source: COVID-19 Vaccine Tracker

In Indiana, the vaccination centers are adding Krogers Grocery Stores. Each store will be provided a large set of vaccines. So I expect that at least in our state, vaccination rates will continue to grow substantially.


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