Preliminary Autistic older adult health study

Post Reply New Topic

In the 1990s, the prevalence of autism spectrum disorder (ASD) among children rose sharply. These children are now entering adulthood, yet physicians and scientists know very little about the health outcomes they might face. Most studies of health have focused on children and adolescents.

However, new research published this week by scientists at the University of Wisconsin­­–Madison found that older adults with ASD may be at greater risk than people without the disorder of developing several health problems, including cardiovascular, urinary, respiratory and digestive issues.

“This is one of the few studies to look at health problems in a primarily middle-aged and older population of individuals with ASD,” says lead author, Lauren Bishop-Fitzpatrick.

With colleagues, Bishop-Fitzpatrick, assistant professor of social work and a researcher at the UW–Madison Waisman Center, used machine learning – a form of artificial intelligence – to analyze de-identified electronic health records of individuals who had received healthcare from the Marshfield Clinic in central Wisconsin and have since passed away.

They analyzed the health records of 91 individuals with ASD and more than 6,000 individuals without ASD from the same region as comparison. The ratio of patients with and without autism was roughly equal to 1:68, the most recent rate of ASD prevalence in the United States as calculated by the Centers for Disease Control and Prevention.

The researchers found that individuals with ASD had increased risks of developing several health complications, including various cardiovascular issues, hypothyroidism, and other neurological issues. They were at decreased risk of alcohol abuse, hypertension, and of developing metastatic cancers.

Based solely on information from patients’ electronic health records, the researchers were also able to independently predict with 93 percent accuracy whether or not a specific individual had ASD.

The researchers hope their findings will lead to larger, more comprehensive studies that focus on the health issues faced by older individuals with ASD. Bishop-Fitzpatrick also plans to speak to individuals with autism and their families to understand their individual health issues and concerns at the same time that she works to understand these at the population level.

Her study co-authors include UW–Madison colleagues Arezoo Movaghar, David Page, Leann Smith DaWalt, Jan Greenberg, and Marsha Mailick,, as well as Murray Brilliant, of Marshfield Clinic.