Study: Hydroxychloroquine and azithromycin reduce COVID19

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Noca
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19 Mar 2020, 5:14 pm

Study finds Hydroxychloroquine and azithromycin reduce COVID19 duration.

There is a graph in the link comparing the two treatments and the control.

https://techcrunch.com/2020/03/19/frenc ... -duration/

A new study whose results were published in the International Journal of Antimicrobial Agents has found early evidence that the combination of hydroxychloroquine, a popular anti-malaria drug known under the trade name Plaqenuil, and antibiotic azithromycin (aka Zithromax or Azithrocin) could be especially effective in treating the COVID-19 coronavirus and reducing the duration of the virus in patients.

The researchers performed a study on 30 confirmed COVID-19 patients, treating each with either hydroxychloroquine on its own, a combination of the medicine with the antibiotic, as well as a control group that received neither. The study was conducted after reports from treatment of Chinese patients indicated that this particular combo had efficacy in shortening the duration of infection in patients.

The patient mix included in the study included six who showed no symptoms whatsoever, as well as 22 who had symptoms in their upper respiratory tract (things like sneezing, headaches and sore throats, and eight who showed lower respiratory tract symptoms (mostly coughing). 20 of the 30 participants in the study received treatment, and the results showed that while hydroxycholoroquine was effective on its own as a treatment, when combined with azithromycin it was even more effective, and by a significant margin.


These results represent a limited study with a small number of patients, but they are promising, especially when combined with earlier reports from patients in China with the same treatment options. Researchers globally are testing a number of potential treatments, including a range of drugs used previously in the efforts to combat Ebola, SARS, HIV and other global outbreaks.

There are no confirmed effective treatments specifically for COVID-19 to date, but regulators and medical researchers everywhere are working hard to get through the process of testing and approvals in search of something that can at least reduce the duration or severity of symptoms in patents. Vaccine development is also underway, but any approved and effective COVID-19 vaccine is at least 12-18 months away, even with resources redirected towards developing one as fast as is safety possible.



Bravo5150
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19 Mar 2020, 5:27 pm

Any idea on how long after making this Discovery will it take to see a dent in the rising stats?



Noca
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19 Mar 2020, 7:41 pm

Bravo5150 wrote:
Any idea on how long after making this Discovery will it take to see a dent in the rising stats?

From what I've read it helps decrease the duration of COVID19 and it's best taken upon onset of symptoms. Because of the incubation period, all the cases you see today are a result of actions 1 to 2 weeks ago.

The average time to stop shedding the virus is 20 days since the day of infection but serious cases may take up to 37 days. This will reduce those lengths of time but it also depends on the ability to do more tests to see who has the virus as well as social distancing in order to slow the the spread of the virus.

You won't see any results from action taken today for weeks.

There is also the problem that there is now supply shortages of Hydroxychloriquine following the release of this study. The good news is it's a generic medication that is off patent so that any drug manufacturer can make it(it's also cheap). If it turns out to be really effective, no doubt drug companies will massively up production, which they would have had to have done anyway.