Good God, about the ibuprofen. Cannabinoids are chemically similar or identical to neurotransmitters in the brain. Ibuprofen is a designer drug that is based on the same tricyclic molecular structure as cannabinoids. When I leave through the Physician's Desk Reference I see this structure repeated with many variations.
Designer drugs are infamous for unpredictable psychotropic effects. I'm not surprised that an artificial cannabinoid can cause rage in some people.
I have rages that are usually related to someone's willful stupidity. Like, when someone's car's electrical system has problems, she wants me to fix them and lets me fix them, but when I inform her that her battery needs to spend time on the charger she suddenly knows a whole lot more about the subject than I do.