How far is it that you're traveling? What are the accommodations like?
I don't know a lot about your specific situation but I had my own situation where until this year I had never left the continental US. I live in the midwest/east coast split, have been to Canada at most, more recently got a job which does more traveling which may have helped. Regardless I booked a trip last summer, for this past January, to spend two weeks in Australia and New Zealand and hit four different major cities. My idea was that I wanted to cross the equator, go somewhere real interesting, and do it while I still had the money. As that trip was coming up it still didn't feel quite real, when I got from Cleveland Hopkins to LAX I was a little nervous but okay, I knew for sure it was happening when I got on the Qantas flight, and once I actually got to Australia (Goldcoast) unfortunately I had been up for more than a day - can't sleep on planes, and had to drag everything around with me for a couple hours because the hotel wouldn't let me check in till 2:30 PM. Mind you - I took this trip by myself, none of my friends had the money to join me.
What I've found to be true is that this kind of thing, first time with anything big as an adult, can be a little daunting. On the other hand though when you actually get to your destination, get the rental car or shuttle, and get to where you need to go - that feeling will lighten up considerably.
_________________
The loneliest part of life: it's not just that no one is on your cloud, few can even see your cloud.