How do I overcome this anxiety over health ?

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In my case, I don't actually worry that right now at this moment in time that I have got a serious health problem and I am not ringing up emergency services or the GP. In my case I just worry about something bad happening to me in the future when I know clearly that everyone's lives are uncertain and never know how long they have to live but seem to have this ridiculous fixation that by certain age I'll all of a sudden be hit with something serious. This has come about from having experienced my colleague passing away suddenly at 50, another colleague having a heart attack at 33 and is now in an almost brain damaged state, my dad had a mini stroke at 48 and his mum (my nan) has diabetes and had some heart attacks in the past and had several bypass operations.

I just really find hard to rationalise and look at the risks and convince myself that I am more likely to be killed in a car crash at my age than have a heart attack. But there is always a part of my brain that contradicts the rational like a devil telling me something in one ear and an angel telling something else in the other.

You sound like you have health anxiety. Which is a valid form of anxiety and something which can require treatment.

Tell your GP that you have health anxiety and would like a referral to someone in mental health that you can have therapy with perhaps, and following that, later down the line, you might seek anti-anxiety meds or antidepressants which can help with anxiety, if you don't already use them.

Stuff happens......all you can do is..the best you can .. perhaps make physiology and methods necessary for
addressing various potential health concerns that might be part of your heredity.(a special interest)... ..And also perhaps allowing you to live a longer healthier life . And eventually you maynot be able to circumvent the enevitable.
As many aspies are said to be accident prone . Be careful not to engage high risk activities, at least without considering potential possible downfalls .
( all a person can do is the best they can)

Actually, you are more likely to die from a heart attack than you are from a car crash, even at your age.

Time and again, whenever I've asked google who and what age groups are at risk of heart attacks ?, Though its not always universal, I nearly always get the same answer from Mayo Clinic saying that men aged 45 and older and women aged 55 are more likely to have a heart attack than younger men and women. Smoking and exposure to tobacco smoke increases the risk but I don't even smoke.

One in six deaths in the US is due to heart disease. One in 93 deaths is due to car accidents.

Now its one in six across the board, and you may have health and living factors which bring your likelihood in any given year at your age as well below 1 in the 6.

However, you do not drive, correct? Given that, you are much less likely to be in the 1 in 93 perish in a given year in an automobile accident than you are if you did drive regularly.

That's my thinking.