Caffeine can be processed differently by different people; like any psychotropic substance (and caffeine technically falls under this umbrella), physiology must be considered. Liken it to alcohol: some people have naturally higher tolerances or can process it faster than the rest, or have "trained" their body on higher levels. Any drug, if taken regularly, with decrease in effectiveness for the same dose. Caffeine actually blocks certain receptors and activates others, almost replacing certain hormones produced. You would become dependent on it for normal function, which is why quitting anything cold-turkey is physically difficult.