interesting discussion. as far as illicit substances are concerned, i used many of them in my much earlier life prior to being diagnosed. I didn't know what was wrong with me, but I felt horrible, and some of them helped me feel better (for a time, and others made me feel worse). Nowadays, I stay away from everything illicit (illegal), and only take what's prescribed for me, as those drugs help me enormously.
I think I also have a high tolerance for meds. Certainly local anesthetics, but for pain as well, and that's a problem. I stay away from alcohol nowadays too, as I tend to want to continue to drink after having a few, and it also makes me feel (further) out of control.
I guess bottom line for me now I stay away from them, as my sanity is somewhat delicately perched at this point since I'm recently diagnosed and on new meds without any additional interference from other drugs or alcohol. And even though you may not feel drunk after 1-2 drinks/hour, you certainly are, and certainly would test it if breathalized. So dear God don't drive. You probably already knew that, so apologies for the likely unnecessary reminer
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Nothing witty here...