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Snowy Owl
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11 Mar 2025, 9:57 am

I watched a video about the positive effects of nicotine. A nicotine patch between the shoulder blades of autists has been linked to lessened symptoms. I started smoking in 2006, right around when I became an entirely different person: not locked inside of myself as much. I became a little more outgoing. I didn’t make the connection until I saw the video. I thought it was just life choices that opened me up. New jobs, different countries. I didn’t think about the nicotine.



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11 Mar 2025, 10:11 am

That is entirely plausible.

One of the interesting things about effective drugs is that a drug makers are initially looking for anything that makes it worse or better. They discard drugs that have no effect. But if it makes it worse it may have some potential as it is doing something.



Edna3362
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11 Mar 2025, 10:18 am

What internal noise or stiffness (or indirectly, due to external noise or forms of rigidity/poor transitioning) of yours does nicotine quiets down or ease over?


If it's not anything else but losing anxiety, then I'm not interested. :lol: (But it will certainly interest a lot of other posters and lurkers)


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Bestiola
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11 Mar 2025, 11:26 am

There is no proof it helps people with ASD, but it might give you nightmares or indigestion, among other things:

Quote:
Nicotine Patch Therapy: Research studies have uncovered abnormalities in nicotinic acetylcholine receptors in the brains of people with autism, and some scientists have posited that core symptoms of ASD could be attributed to these alterations. Some findings specifically indicate a shortage of these receptors, leading some to believe that stimulating or increasing these receptors could eliminate ASD symptoms. Proponents of nicotine patch use in individuals with ASD believe that the nicotine released into the body from the patch activates and upregulates receptors, and thereby reduces ASD symptoms. Despite having a rationale that is based on scientific findings, use of this treatment is not supported by scientific evidence. No clinical trials have demonstrated that nicotine patches are safe or effective in the treatment of ASD. Common side effects reported in clinical studies evaluating safety and efficacy of the patches include skin irritation; sleep problems, including insomnia and nightmares; headaches, indigestion, and nervousness.

https://autismsciencefoundation.org/bew ... reatments/

What they did "prove" is that one very irritable patient with ASD, who also happened to be a teenager, had fewer issues with anger management when having nicotine patches.

https://link.springer.com/article/10.10 ... 015-2471-0

Regarding smoking it, it's perfect if you want to get cancer, stroke, heart attack etc.


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11 Mar 2025, 12:19 pm

Bestiola wrote:
Regarding smoking it, it's a perfect if you want to get a cancer, stroke, heart attack etc.


Yes, most parents are looking for a safe and effective treatment.

Nicotine is an effective way to organically control insect pests but not very safe so it is prohibited from organic food production.



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11 Mar 2025, 5:28 pm

Never used a patch, but I've vaped a lot of nicotine and chewed a lot of nicotine gum. Never noticed any effect on my ASD, though I've never been without nicotine for long enough to know whether ASD gets any worse without it.

I would imagine that nicotine is mildly carminative (especially once you're addicted), and that it's easier to perform well when you're relaxed.

Nicotine is supposed to raise the blood pressure but I've not seen any evidence for that in my own case. Otherwise I'd make more effort to get off it. They charge a lot for the gum, but I'm addicted, and so far I've been able to afford it.

I'm not sure it's ethical to try treating ASD with nicotine, given how addictive it is, but maybe that's the idea - get 'em hooked, sell 'em nicotine for the rest of their lives. No, that's too cynical. At least I hope it is.



lostonearth35
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12 Mar 2025, 12:47 am

I have never smoked in my life unless you count all the times it was second hand from my dad and other adults. And I hated it.

I once read that nicotine can supposedly relieve the symptoms of schizophrenia. When I lived in the group home where most of the residents had chronic schizophrenia they smoked like chimneys. And they were allowed to do this indoors in a "smoking room", but by the end of the 90s virtually everyone knew that the smoke gets everywhere and poisons everyone and everything it touches. The walls in the room would be yellow from cigarette smoke. It was disgusting.

I don't if nicotine really does help autism or schizophrenia, but if it does people should just wear patches instead of inhaling that garbage. But you've got to love how clueless parents would rather get their kids on a highly addictive drug while thinking vaccines are dangerous and evil. :roll:



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12 Mar 2025, 3:23 pm

Caffeine is my drug of choice. It has an overall great effect on my general well-being. Any research suggesting it has any impact on autism?


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Bestiola
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12 Mar 2025, 3:42 pm

Hmmm:

Quote:
Coffee and Autism: Potential Benefits
While research is still ongoing, some individuals with autism and their families report experiencing potential benefits from coffee consumption. One of the most commonly reported benefits is improved focus and attention. The stimulant properties of caffeine may help some individuals with ASD to better concentrate on tasks and filter out distractions, which can be particularly challenging for those on the spectrum.

Caffeine’s potential mood-enhancing effects have also been noted by some individuals with autism. The increase in dopamine levels associated with caffeine consumption may contribute to feelings of well-being and improved mood in some cases. However, it’s important to note that these effects can vary greatly between individuals, and what works for one person may not work for another.

The antioxidant properties of coffee have garnered attention in recent years for their potential health benefits. Some researchers speculate that these antioxidants could potentially impact autism symptoms by reducing oxidative stress and inflammation in the brain. While this area of research is still in its early stages, it presents an intriguing avenue for future studies.

https://neurolaunch.com/caffeine-and-autism/


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Edna3362
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12 Mar 2025, 5:53 pm

Caffeine doesn't work for me. Not even for helping me wake up.

Unless I took enough hormonal birth control pills and limit it to 1 per 3+ days, all I get are side effects, and immediate headache even if I drank 2 days in a row and stopped.


Otherwise, I like the taste of beverages enough to have them in varying ways. Including black coffee and lots of chocolates.


But yes, I do need an anti-inflammatory.
Yet I needed more than just the anti-inflammatory of the brain, because the other (chronic) inflammatories I have will affect my brain.


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12 Mar 2025, 6:15 pm

Caffeine: I can see the potential benefit for some, though I guess it's rather nonspecific - stimulating the brain so it can work faster and better. Probably a bit like amphetamine, but not so strong.

It's probably worth a go, but I'd advise monitoring blood pressure if you start taking a lot of caffeine. On average you might see a 4mmHg rise in systolic blood pressure from 250mg of caffeine, which isn't much, but individual sensitivity varies widely. I suspect my blood pressure is somewhat sensitive to caffeine. Certainly it has a pharmacological effect if the dose is high enough.

In my youth I used to take quite a bit of the stuff in the form of Beecham's Hot Lemon Powders, to pep me up when I played at gigs or went to late-night parties (in those days they contained caffeine), until one time when my heart started thumping and I broke into a cold sweat, which scared me. After that experience I stopped being so reckless. I sometimes use a bit of caffeine these days, but I don't take more than about 200mg. Caffeine seems to help me, but I now understand the importance of sticking to a moderate dose. It's a great shame, the first time I tried a high-ish dose I felt the benefit. Don't know whether it reduced my ASD traits or not. In those days I hadn't even heard of ASD.



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12 Mar 2025, 7:18 pm

I used to vape constantly. Like constantly constantly. I think it messed up my lungs a bit. I don't know what traits of awetism nicotine is supposed to help ameliorate, but I will have none of it. I rather be extra autistic than addicted to that damn vape that I was either stressed about losing or charging and the financial costs. If you can stick to the patch and it helps, that would be interesting but dangerous.


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Edna3362
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12 Mar 2025, 8:24 pm

I can't smoke. Not even vape. Because crappy respiratory system and it'll worsen it.

Not really the lungs and mostly the nose, which is chronically inflammed for no apparent reason for the last 20+ years untreated until recently.


I can try a patch. I just had to decide when to try them and learn more about it beforehand.

Only and only because I'm a consenting adult (and not even a young adult anymore) who can chose to have an informed decision when it came to the risks in the effects of self medicating.


So what does nicotine ease out over autism?
Or even a secondary effect from being autistic (from sensitivities, from external stressors) ?



I'm also someone who doesn't have any reliable external consumable until recently.

Nicotine isn't high on my try it list unless I try out all the adaptogens and supplements I can afford.

With added layer of needing birth control pills (or rather, possibly enough estrogen on my body) to make said supplements effective...
Something is just suspicious with the way my body "naturally" metabolizes stuff.


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13 Mar 2025, 12:07 am

My mind takes well to stimulants like caffeine and nicotine. I find that when I consume them I can concentrate much better.

I used to live close to a coffee shop that allowed people to smoke on their patio. When I walked down to the coffee shop I would bring a book and a few small cigars. I found that the combination of nicotine and caffeine would help me concentrate on reading.

I also found that stimulants helped with burnout and depression, I felt a overall feeling of being awake, alert, and sharp which is a sensation I do not feel often naturally as an adult.



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13 Mar 2025, 9:50 am

Edna3362 wrote:
So what does nicotine ease out over autism?
Or even a secondary effect from being autistic (from sensitivities, from external stressors) ?


According to two reports linked below that I found using Google Gemini, nicotine might improve sleep, reduce aggression and irritability for those diagnosed with ASD. However, it's important to be aware of considerable limitations with both of the reports. One of them is a report on a single adolescent that was hospitalized due to behavioral problems such as aggression towards other, self-injurious head-banging and biting. That is no where near enough participants to make any valid conclusion since the there could have been millions of reasons why nicotine helped reduce their aggression apart from them being autistic. The other study had an effective sample size of seven. All of the participants were prescribed anti-psychotics and/or mood stabilizers to reduce their aggressive behaviors. So for all we know, maybe the nicotine had an interaction with the medications, there were situational factors that were leading the participants to act aggressively (not autism itself), or maybe nicotine helped reduce aggression in these specific individuals for some other reason the researchers were not aware of.

Reduction of Aggressive Episodes After Repeated Transdermal Nicotine Administration in a Hospitalized Adolescent with Autism Spectrum Disorder

An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder


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Participant626
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13 Mar 2025, 9:54 am

Canadian Freedom Lover wrote:
My mind takes well to stimulants like caffeine and nicotine. I find that when I consume them I can concentrate much better.


Same! Vaping really helped with feeling stable and being able to pay attention. I would drink espresso and vape the entire time like it was a medical necessity. Luckily, I came off of the vape using Chantix, and now I'm properly medicated for ADHD, so I don't vape anymore. It was destroying my lungs and made it so I had to have my vape with me literally all the time. I couldn't even go to bed or use the bathroom without it. Going to places in which I couldn't vape for a few hours made me quite anxious and I would avoid them if possible.


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