Bone marrow is linked to autism?

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This post gathers a lot of information.

Although it really wouldn't have hurt to throw in some sources.

My wife has CFS. It sucks big time. You have my sympathy.



Point taken.



The original article you referenced was very interesting. It looks like it is opening up some promising lines of research. My first question is if the protein profiles they discovered are cause or effect. To use a crude analogy, a population of one legged people can't run that well. Clearly, the missing leg is an issue, but the cause is not the missing leg. The cause is what brought about the missing leg.

What those proteins may be pointing to is the specific underlying genes that are being expressed in anomalous ways, either through mutations, environmental stressors or both.

Last edited by wavefreak58 on 21 Dec 2010, 9:26 am, edited 1 time in total.

I'm sorry people have made a mess of your thread. I, for one, find this quite interesting.

I'm hoping I won't ever need a bone marrow transplant, but if I do, I'll let you know how that goes.

>>> Like the Wendies Commercial where humans run into a black hole, and their legs swing back and forth as they fall down, as if they're still running. That commercial is funny.

bone marrow has been found to be linked with "life" as well.

i think you have the answer.
after much consideration, i am sure that if my bone marrow was sucked completely out of my skeleton, then within a short amount of time i would no longer be autistic.


autism is not a part of heaven.

Overexposure to whale feces causes autism.

What were you doing crawling about in a whales butt?

Life causes death. Every single person who died has been alive.

Hi wavefreak58

I am not sure which proteins you meant?

There is a huge mystery behind what kicks off and sustains chronic microglial activation. There are probably many causes. Interestingly, infection and inflammation in the gut can kick of brain inflammation / chronic microglial activation directly, even though the gut and brain are distant organs. The gut and the brain are in communication via various links: the vagus nerve, and inflammatory cytokines traveling in the blood are two such links.

Another interesting example: high homocysteine levels seems to cause a ramp up in brain inflammation / chronic microglial activation. And would you know it: high homocysteine is often found in autism - again suggesting that it is this chronic microglial activation state that may well be instrumental in creating the symptoms of autism.

Homocysteine levels can be lowered with folic acid, vitamin B6, and cyanocobalamin (vitamin B12).




A nice easy-reading reference on brain inflammation in general, brain inflammation's connection to neurological conditions, and ways of treating and reducing excessive brain inflammation using safe dietary supplements is here (just Google search on the bold words to find the web site - I still can't post links):

sickness syndrome five step program

This one might help lots of people; the supplement suggestion definitely helped me get a calmer state of mind.


More scientific refs:

Role of Microglia in Central Nervous System Infections

Microglial activation and increased microglial density observed in the dorsolateral prefrontal cortex in autism

Chronic Microglial Activation and Excitotoxicity Secondary to Excessive Immune Stimulation: Possible Factors in Gulf War Syndrome and Autism



Note that all this stuff on chronic microglial activation and CFS / autism / GWS is an established line of research. My little hypothesis on a possible bone marrow connection to CMA is just an added speculation purely of mine.