What medication (if any) are you on and what does it help?

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Celexa is helping my anxiety. This is the second time I have taken it, and the first day I felt great, then for the next two or three days my anxiety reached uncomfortably heightened levels, previously unknown to me, after which I stabilised.

Seroquil for anxiety (and better clarity of thought) and Abilify for depression (with Efexor.) If I wasn't able to take them I would quickly become self-destructive.

Sertraline (better known by its commercial name "Zoloft") has worked wonders for me. I sleep better and think more clearly with it; it takes away some of the anxiety common to autism, and allows for smoother social functioning. I have experienced none of the weight gain associated with SSRI antidepressants, and though I do feel "robotic" so to speak, I was like that already. Then again some research suggests that a placebo works just as well as any antidepressant, but even so, whatever works right?

One criticism of that research is that it includes people with mild depression. That is, if you remove the mild and moderate cases antidepressants do show a statistically significant benefit.

I haven't read all there is to read on the subject, but the meme that antidepressants don't really do anything appears to be fudged at least a little, IMO. I think it may be a case of various people having an anti-psych-drug agenda.

Anyway, that said, I take amitriptyline and mianserin for depression and they do help. I'd say the drugs help 50%, but also allow other things which did nothing when I was totally depressed to be helpful, i.e. "mindfulness," relaxation exercises, taking walks, hobbies, etc.

I recently tried gabapentin for sleep and restless legs induced by the above meds, but it seemed to cause a depressive crash. I also take sometimes midrodrine for dysautonomia.

I take Wellbutrin for depression and it seems to help, other than bringing out my stims more. I notice that my leg bouncing has gotten to be a most of the time thing with it.