My Theory of Asperger's and it's Root Cause

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Do you buy into this theory? (Read entire post before voting)
100% - Yes, I agree with you, that must be the root cause of Asperger's 2%  2%  [ 1 ]
75% - Most likely true, but there may be other causes as well. 17%  17%  [ 10 ]
50% - I am not sure, you may be right, or you may be wrong. 31%  31%  [ 18 ]
25% - There is some truth to what you are saying, but most likely it is something else. 50%  50%  [ 29 ]
Total votes : 58

kojot
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25 Mar 2012, 1:43 pm

idlewild wrote:
I find it interesting that you are so confident of your theory you didn't give a 0% option in your poll.


That was my first thought too xD



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25 Mar 2012, 3:02 pm

and me



rdos
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25 Mar 2012, 3:24 pm

Any theory that proposes that the central issue in AS is a dysfunction is wrong with 100% confidence. This cannot be so, as AS is much to common to primarily be a dysfunction. So I'll select the 0% alternative.



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25 Mar 2012, 3:47 pm

rdos wrote:
Any theory that proposes that the central issue in AS is a dysfunction is wrong with 100% confidence. This cannot be so, as AS is much to common to primarily be a dysfunction. So I'll select the 0% alternative.


Your logic defies me.



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25 Mar 2012, 3:56 pm

rdos wrote:
Any theory that proposes that the central issue in AS is a dysfunction is wrong with 100% confidence.


That's exactly how I feel about hypotheses that aim to make autism into some kind of superpower. Anyway, nobody called AS a dysfunction. It is a developmental neurological disorder, which is not quite the same.

Quote:
This cannot be so, as AS is much to common to primarily be a dysfunction. So I'll select the 0% alternative.


Approximately 1 in 100 children have AS. The exact same number of children suffer from scoliosis. Both are disorders. Neither condition constitutes a normal development.

PS: I suffer from both, and my AS has caused me a LOT more problems than my scoliosis.



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25 Mar 2012, 4:01 pm

Dysfunction is... not quite right, yeah. Dysfunction implies that some aspect of an otherwise typical brain is not working as well. If you apply that to autism, you can say that I have a "sensory integration dysfunction" or a "face-reading dysfunction" but you can't call autism itself a dysfunction because it really isn't. It's not a dysfunction of a typical brain, but a brain that is entirely different. There's more to autism than just being bad at one thing or another; you have additional traits that NTs don't have, both drawbacks and advantages and neutral differences. Dysfunction is something you could say about a specific skill but I wouldn't apply the word to autism in general.


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25 Mar 2012, 4:22 pm

CrazyCatLord wrote:
rdos wrote:
Any theory that proposes that the central issue in AS is a dysfunction is wrong with 100% confidence.


That's exactly how I feel about hypotheses that aim to make autism into some kind of superpower. Anyway, nobody called AS a dysfunction. It is a developmental neurological disorder, which is not quite the same.

Quote:
This cannot be so, as AS is much to common to primarily be a dysfunction. So I'll select the 0% alternative.


Approximately 1 in 100 children have AS. The exact same number of children suffer from scoliosis. Both are disorders. Neither condition constitutes a normal development.

PS: I suffer from both, and my AS has caused me a LOT more problems than my scoliosis.


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Vito
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25 Mar 2012, 4:48 pm

I disagree, I once read in some high school psychology textbook, that there were even some studies on people who have got, somehow, inhibited the function of the corpus callosum to the point that hemispheres were not able to communicate at all. While these individuals were unable to solve certain types of problems (for example, they got covered one eye and then got presented problem which could be solved only by a hemisphere of the eye covered - they were unable to solve it), during daily life, they did not display any significant problems and definitely not any behaviors that could be associated with AS/ASD.

Therefore, while am I sure that functions and cooperation of hemispheres are interesting and important, I think they have nothing to do with Autism or Asperger's



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25 Mar 2012, 5:06 pm

Vito wrote:
I disagree, I once read in some high school psychology textbook, that there were even some studies on people who have got, somehow, inhibited the function of the corpus callosum to the point that hemispheres were not able to communicate at all. While these individuals were unable to solve certain types of problems (for example, they got covered one eye and then got presented problem which could be solved only by a hemisphere of the eye covered - they were unable to solve it), during daily life, they did not display any significant problems and definitely not any behaviors that could be associated with AS/ASD.

Therefore, while am I sure that functions and cooperation of hemispheres are interesting and important, I think they have nothing to do with Autism or Asperger's


Having the corpus callosum removed is sometimes done to treat severe epilepsy.
Yep, no aspsie traits are seen to develop.



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25 Mar 2012, 5:38 pm

CrazyCatLord wrote:
You are halfway there. Autism is indeed caused by insufficient communication between different parts of the brain, but not in the way that you think. The human brain consists of more than just two parts. We have a so-called triune brain with three main regions that have evolved at different times in the history of animal life. Below is a very simplified schematic:

Image

The reptilian complex is the oldest structure and controls muscle functi ... blah blah blah boring conversation anyway LUKE WERE GONNA HAVE COMP... ection between the hemispheres that causes AS, but rather a poor connection between the frontal lobe and the remaining brain.

M. Murias et al disovered that in people with Asperger's, the frontal lobe has weak functional connections with the rest of the cortex, whereas there is an overconnectivity within the frontal lobe itself (link). According to Murias, this could result in "local, rather than global information processing". This explains both the increased intelligence in some individuals with AS as well as our poor emotional competence and motor control. I suppose that the main difference between AS and classic autism is a better neural connectivity between the frontal lobe and the left cortical hemisphere, which controls speech and language.


"Reptilian Brain?" I want what your smoking.
However, the point you make about the frontal lobe makes alot of sense, perhaps it is an even better theory than my own, I will take that into consideration.
However, evolution is simply wrong.

WhiteWidow wrote:
I am more than intrigued. You make me want to take neuroscience courses.

I think that our brain produces sets of algorithms at a consistent pace

I would make AS my thesis if I did take neuroscience as a course. I still believe the CAT/MRI scanning is still a good idea to prove, disprove the theory.

Poke wrote:
kojot wrote:
Lobber wrote:
Human beings have two brains. Two separate and distinct brains. Yes, that is right. We have not one, but two brains. Each hemisphere is in fact, a self contained brain in its own right. ...


I've stopped reading after this. This is total BS. Please learn about basic neurobiology.


A proper understanding of brain lateralization requires the utilization of generalities. Lobber extrapolates them too far, while kojot has been intellectually groomed to reject them. Both are wrong.

Could you give an example of a correct theory?

kojot wrote:
I just don't like "theories". I like science. "Theory" based on BS is a waste of time.

So if you don't like "Theories", does that mean you don't like the "Theory" of Gravity? Or the "Theory" of Relativity? Or even the "Theory" of Evolution? (It isn't a fact, it's a "Theory." Probably the most BS "Theory" mentioned in this thread).

kojot wrote:
idlewild wrote:
I find it interesting that you are so confident of your theory you didn't give a 0% option in your poll.


That was my first thought too xD

This is incorrect.

I did give a 0% option in the poll.

However, I realize now that I misunderstood how adding options work, and thought the 0% option was added when I hit submit, instead of adding the last option and having a 6th blank option left underneath it. User error.

rdos wrote:
Any theory that proposes that the central issue in AS is a dysfunction is wrong with 100% confidence. This cannot be so, as AS is much to common to primarily be a dysfunction. So I'll select the 0% alternative.

Do you have anything to back this assertion up? Or is it simply your pride that makes you say this?
Callista wrote:
Dysfunction is... not quite right, yeah. Dysfunction implies that some aspect of an otherwise typical brain is not working as well. If you apply that to autism, you can say that I have a "sensory integration dysfunction" or a "face-reading dysfunction" but you can't call autism itself a dysfunction because it really isn't. It's not a dysfunction of a typical brain, but a brain that is entirely different. There's more to autism than just being bad at one thing or another; you have additional traits that NTs don't have, both drawbacks and advantages and neutral differences. Dysfunction is something you could say about a specific skill but I wouldn't apply the word to autism in general.

Of course autism is a dysfunction of the brain. If it isn't a dysfunction, what is it? Every neuron is simply "out to lunch?" A basic lack of connectivity of the speech centers of the brain to the frontal lobes, resulting in a person who is mute, doesn't have a "Entirely differently wired brain" but a dysfunctional connection between the frontal lobes and the speech centers.

Vito wrote:
I disagree, I once read in some high school psychology textbook, that there were even some studies on people who have got, somehow, inhibited the function of the corpus callosum to the point that hemispheres were not able to communicate at all. While these individuals were unable to solve certain types of problems (for example, they got covered one eye and then got presented problem which could be solved only by a hemisphere of the eye covered - they were unable to solve it), during daily life, they did not display any significant problems and definitely not any behaviors that could be associated with AS/ASD.

Therefore, while am I sure that functions and cooperation of hemispheres are interesting and important, I think they have nothing to do with Autism or Asperger's

I can disprove this theory as well. Those people who had their corpus callosum cut in half rendering their two brains independent of one another had already developed brains since they were already a certain age when the surgery was completed. Therefore, their brains had already learned 90% of the wiring that takes place in the first three years of life. If they had the surgery during the first three years, then lets see how aspergy they become. Otherwise, the brains are already capable of being neurotypical.


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25 Mar 2012, 6:57 pm

CrazyCatLord wrote:
Lobber wrote:
Human beings have two brains. Two separate and distinct brains. Yes, that is right. We have not one, but two brains. Each hemisphere is in fact, a self contained brain in its own right. These two entities communicate with each other primarily through a structure seated deep inside the brain called the "corpus callosum." It is my belief and personal opinion at this point in time, that the root cause of Asperger's is a result of an underdeveloped or improperly wired corpus callosum.

To put it in plain english, Aspies brains cannot communicate with each other properly. ....


You are halfway there. Autism is indeed caused by insufficient communication between different parts of the brain, but not in the way that you think. The human brain consists of more than just two parts. We have a so-called triune brain with three main regions that have evolved at different times in the history of animal life. Below is a very simplified schematic:

Image

The reptilian complex is the oldest structure and controls muscle function, balance, and autonomic functions such as heartbeat and breathing. The limbic system (a.k.a. paleomammalian complex) is responsible for your emotions, urges and instincts. It handles things like pain and pleasure, fear and aggression, appetite, sex drive, sleep, smell, and emotional memories. It would be possible for us to function with these two brain areas alone, and many lower animals do just that.

Finally, there is the (neo)cortex, a.k.a neomammalian complex, which is unique to mammals. This is your conscious brain that controls intellectual, cognitive activity and stores more complex memories. It is this part that is split into a left and right hemisphere. Of course this is still a very simplistic model. In reality, each of the three brain areas (or four, if you count the neocortex as two hemispheres) are again split into several sub-structures that are specialized on different tasks, but I don't want to get lost in details.

To sum it up, the reptilian brain controls basic body functions like breathing, the limbic system is the seat of emotions, and the neocortex hosts your consciousness and intellect. What separates humans from other mammals is the enormous size of our frontal lobe, which is part of the neocortex. Most of our conscious thought happens in the frontal lobe. Or rather, the frontal lobes, seeing that the lobe is divided into two hemispheres like the rest of the cortex. But it is not a lack of connection between the hemispheres that causes AS, but rather a poor connection between the frontal lobe and the remaining brain.

M. Murias et al disovered that in people with Asperger's, the frontal lobe has weak functional connections with the rest of the cortex, whereas there is an overconnectivity within the frontal lobe itself (link). According to Murias, this could result in "local, rather than global information processing". This explains both the increased intelligence in some individuals with AS as well as our poor emotional competence and motor control. I suppose that the main difference between AS and classic autism is a better neural connectivity between the frontal lobe and the left cortical hemisphere, which controls speech and language.


Maybe a interface in connection between one area of the brain and the rest means that there is more likely to be more areas with disconnections?


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25 Mar 2012, 9:05 pm

If your theory was correct, people with agenesis of the corpus callosum would virtually all be autistic. Instead, while their cognitive profile overlaps with autism in some ways, only 8.5% are autistic (which is higher than the general population, but still pretty low).



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25 Mar 2012, 9:40 pm

Actually, to be TOTALLY accurate, this is *NOT* a Theory. This is an Hypothesis. It can be tested & proved or disproved.
OK, now I have had my daily Anal retentive moment of the day, you are kindly returned to the thread now in progress...
*********************************
I think you are headed in a general direction toward something here, but...
These models of the human brain are rather simplistic & a bit dated, though not totally untrue. And the deepest, oldest part of our brains are indeed often refered to as "reptilian". There was nothing drug induced about that reply.

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25 Mar 2012, 9:49 pm

Its not actually the first time I have heard the corpus callosum theory. The author of 'Disconnected kids', I forget his name, also believes it is a miswiring of the corpus callosum. He has a talk online somewhere where he talks about it.

I voted the 50% answer. It seems to make some sense, but as others previously pointed out they sometimes severe the corpus callosum in people who have severe epilepsy, but they do not become autistic as a result.



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26 Mar 2012, 9:19 am

Lobber wrote:

This would also explain why Asperger's syndrome can be more severe (though not always necessarily so) in males rather than females, due to the more pronounced specialization of male brains between the right and left halves, versus the more balanced distribution of function as found in female brains. Boys are girls are wired differently after all.


I don't know enough about nothin' to contest your theory but I do agree with this part. I've thought for a long time that my starting out female is what prevented me from becoming a real Aspie. I do have a narrow focus but it's more like what you would see with an NT male, specialized brain but not autistic.

I am still female just to clarify lol...I do have the male 2D/4D ratio but am all woman.


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26 Mar 2012, 1:19 pm

Lobber wrote:
CrazyCatLord wrote:
You are halfway there. Autism is indeed caused by insufficient communication between different parts of the brain, but not in the way that you think. The human brain consists of more than just two parts. We have a so-called triune brain with three main regions that have evolved at different times in the history of animal life. Below is a very simplified schematic:

Image

The reptilian complex is the oldest structure and controls muscle functi ... blah blah blah boring conversation anyway LUKE WERE GONNA HAVE COMP... ection between the hemispheres that causes AS, but rather a poor connection between the frontal lobe and the remaining brain.

M. Murias et al disovered that in people with Asperger's, the frontal lobe has weak functional connections with the rest of the cortex, whereas there is an overconnectivity within the frontal lobe itself (link). According to Murias, this could result in "local, rather than global information processing". This explains both the increased intelligence in some individuals with AS as well as our poor emotional competence and motor control. I suppose that the main difference between AS and classic autism is a better neural connectivity between the frontal lobe and the left cortical hemisphere, which controls speech and language.


"Reptilian Brain?" I want what your smoking.
However, the point you make about the frontal lobe makes alot of sense, perhaps it is an even better theory than my own, I will take that into consideration.
However, evolution is simply wrong.


The term reptilian brain might seem hilarious to you, but that's what the evolutionary oldest part of the brain is commonly called. You can also refer to it as the R-complex, short for reptilian complex, or the cerebellum and the basal ganglia if you like that better. I strongly suggest that you educate yourself on a topic before you start to hypothesize about it. But if you outright reject scientific knowledge, such as evolution, dabbling in the natural sciences is a futile effort for you anyway.

PS: I'd appreciate it if you didn't falsify my quotes. I never wrote anything like "blah blah blah boring conversation anyway LUKE WERE GONNA HAVE COMP". What does the last part even mean? If you want to shorten a quote, just leave the remaining text out or replace it with an ellipsis.

PPS: The next time I come across a "theory" like this, I won't mistake it for a semi-educated debate and truth seeking effort, and invest this much time in an attempt to contribute something worthwhile. I should have simply shot you down for not having the slightest clue what you're talking about, like kojot did.