I have had strange reactions to certain medications, but not others.
The first prescription I was prescribed was Clonidine, for sleep problems. I have never had any problems with Clonidine, as it generally helps with my sleep problems. It doesn't work perfectly; no drug works perfectly 100% of the time. Clonidine sometimes doesn't work if I have a lot of stuff on my mind or if my brain suddenly decides to turn on at 2AM when I have to go to school/work/college the next day. I have to compensate in other ways such as checking Facebook, WP, YouTube, and Twitter.
I took Zoloft for the first few weeks of fourth grade, which was in late 2000, and it made me do things that I would never dare do otherwise (I am not going to say what, but it got me into big trouble), and it also made me extremely lazy in class to the point that I could NOT do any schoolwork at all. I had an aide at the time and even she couldn't do anything about my increased difficulties in class.
My mother paid for a psychatrist and he took me off the Zoloft and put me on Ritalin to treat my ADHD. The first day after starting Ritalin, I did twenty-seven division problems in under five minutes and missed only three of them. That was the first time in life that I did any such assignment that quickly and got that good of a grade. The dreadful Zoloft days were over at last.
By October 2003, I was switched from Ritalin to Adderall. I was warned of the side effects by my PE teacher as they could interfere with my ability to perform in PE. However, I had no such side effects, and it worked just as well as the Ritalin. However, during the summer of 2005, I vomited my breakfast, including my Adderall all over one of my favorite car magazines, resulting in a permanent blue stain on a picture of a Cadillac STS. My mother deemed it unsafe to give me another Adderall, so I suffered from withdrawal symptoms, most notably irratibility. That was the only time I had to withdraw from Adderall for many years.
Adderall didn't cause me any serious issues until the time I started college in a high school program. I was under a lot of stress that year from sudden cuts to public transportation, and increased social difficulties that caused my social network I formed to completely collapse, and I lost all but two friends that I had made during that school year. I know I'm getting a little sidetracked, but the stress I was under at the time might have had some role with the serious issues I would get later from Adderall. By late 2010, I was starting to experience other side effects, most notably a very high level of anxiety, especially social anxiety, which led to quite a few panic attacks, particularly when using public transportation and an irrational fear that if I stood under a fire alarm, it would go off. By 2011, it got a whole lot worse, particularly the week following a SkillsUSA competition. I could barely walk with my backpack on, which was only half-full and I was forced to use EVERY drinking fountain as a pit stop. I had a very big memory lapse during class which frustrated both myself and my instructor to no end. At the end of the week, I went to the doctor for the usual med-check. They needed some bloodwork and they found out that I was dehydrated. I made sure that I drank plenty of water before I left home after that. However, the anxiety and panic attacks didn't stop. By the summer of that year, I guessed that I had developed Social Anxiety disorder. I eventually realized that it wasn't an anxiety disorder at all, but vitamin B complex deficiency, after I started developing a high level of sensitivity to sunlight, most notably my eyes watering up when waiting for the bus. Taking a vitamin B complex supplement with ALL eight B vitamins is necessary to prevent the deficiency. It doesn't help that Medicaid now only covers Adderall for ADHD, at least in the state of Colorado. Adderall works fine for me these days as long as I take a vitamin B complex supplement with it.
I have no strange reactions to most antibiotics, and I did have to go on antibiotics when I caught the flu twice in early 2003, making me miss four weeks of school. I had to make up the dreaded state assessment program tests (CSAP's), but my aide provided certain accommodations.
And last, but not least, some allergy medications, such as Benadryl, make me drowsy to the point that I have an extremely tough time staying awake while riding the bus. The last time I took Benadryl, I had several microsleep sessions while riding the bus to the local community college for my first day of school on the college side. The microsleep sessions were about a half-second each, but noticeable as my hearing cut off and my vision lost focus each time.