Hearing is my strongest sense, and like others above me in the thread have said, it causes me real problems. I can't cope with a room with different people having separate conversations - how great for socialising and work - as it all ends up being one loud 'white noise' mush. I also tend to hear every squeak and creak in the house at night unless I use my ear plugs; even with triple glazing I can hear certain noises outside the house too. Drives me bonkers.
My eyesight is awful, I now have glasses for everyday - driving, TV etc. I also have a separate pair for the Pc and another for reading. I have tried vari-focals, but tripped over just about everything I encountered and envisaged falling down the stairs! The bummer is that whilst my focus is awful, it doesn't stop my light sensitivity issues; come on, can't catch a break....
Another 'sense' I have, and I'm not sure where this sits, but I am extremely sensitive to 'the vibes' or 'the energy' in a room. I'm not sure how to describe it, but I can really tell when something has happened by a feeling left behind in the room. I may not know what, but I know something negative has happened even if the people are sat there saying, "Hey, everything is great!". It can be very wearing at times. Sorry that last one is a bit vague, but I seem to have a hyper-empathy issue! 
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Moomintroll sighed. He felt sad even though he had no real reason to feel that way.