My main obstacle to entrepreneurship is my executive function problems.
I would like to own a business making various arty things (novellas, graphic novels, video games, etc), but making anything good is a LOT of work, even before you get into the business aspect of it.
It's hard for me to even get out of bed in the morning. Or go to bed. Or eat. Or check the mail. Or take out the trash. Bleh.
Social problems wouldn't matter too much, except the usual social anxiety.