Self-Medicating Social Awkwardness with Alcohol

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Shivani
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08 Aug 2007, 5:34 pm

I find if I am invited out to social situations, I actually need a glass of wine or two to reduce my anxiety levels enough to get out the door and go.
I find that I can also communicate better most of the time, if I have a few drinks, depending on the situation.
Not always tho'.



Macbeth
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08 Aug 2007, 5:53 pm

It doesnt hold up that other people being drunk is what makes drinking work. Ive been around drunk people and they will still pick up on aspie "traits" anyway, if i am sober.

A pint or two (average 4.% volume beer) seems to alleviate most of my social anxiety issues. It doesnt solve the facial expressions issue, (reading them or making them) though luckily most drinking is done in loud premises, so the volume and tone of voice issues arent a problem so much.

Basically, a shot of whiskey for "medicinal purposes" is about the right amount.

If someone could isolate the social deinhibitor aspect of booze, without the falling over, vomiting, etc, then aspies would be on a roll :)


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08 Aug 2007, 6:03 pm

Macbeth wrote:

If someone could isolate the social deinhibitor aspect of booze, without the falling over, vomiting, etc, then aspies would be on a roll :)


http://www.nih.gov/news/pr/oct2005/niaaa-03b.htm

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National Institute on Alcohol Abuse and Alcoholism (NIAAA)
EMBARGOED FOR RELEASE
Monday, October 3, 2005
5:00 p.m. ET

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Researchers Shed Light on Anxiety and Alcohol Intake

Scientists have identified a brain mechanism in rats that may play a central role in regulating anxiety and alcohol-drinking. The finding, by researchers supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), could provide important clues about the neurobiology of alcohol-drinking behaviors in humans. A report of the study appears in the October 3, 2005 issue of the Journal of Clinical Investigation.

“This is an intriguing finding,” notes NIAAA Director Ting-Kai Li, M.D. “These experiments, conducted in rats selectively bred to have a high affinity for alcohol, help us address questions about the potential role that anxiety might play in human alcoholism. These molecular studies also may reveal potential targets for therapy of anxiety and alcoholism.”

Some researchers have suggested that high levels of anxiety may predispose some individuals to becoming alcoholic.

Researchers led by Subhash C. Pandey, Ph.D., Associate Professor and director of neuroscience alcoholism research in the Department of Psychiatry at the University of Illinois and Jesse Brown VA Medical Center in Chicago, found that “P” rats, a strain bred to prefer alcohol, showed more anxiety-like behaviors and drank more alcohol, than non alcohol-preferring “NP” rats. They measured anxiety in the rats with an apparatus known as an elevated plus-maze, which consists of two open arms and two closed arms connected to a central platform. Anxiety is gauged as a function of the amount of time a rat spends in the closed versus the open arms of the maze during a 5-minute testing period — the greater an animal’s level of anxiety, the less open-arm activity it displays.

Dr. Pandey and his colleagues also found that levels of CREB, a protein involved in a variety of brain functions, were lower in certain brain areas of P rats compared with NP rats. Levels of neuropeptide Y (NPY), a molecule that regulates the function of several neurotransmitters and is known to play a role in anxiety and alcohol-drinking behaviors, also were lower in P rats. One function of CREB is to regulate the production of NPY.

“Compared to NP rats, levels of CREB and NPY were innately lower in the central amygdala and medial amygdala of P rats,” explains Dr. Pandey, “brain areas which play a crucial role in anxiety behaviors and which have been shown previously to be involved in rewarding, reinforcing, and motivational aspects of alcohol drinking behaviors. And turning off CREB function in the central amygdala of NP rats makes them look like P rats — more anxious and thus more likely to drink.”

Alcohol intake reduced anxiety-like behaviors in the P rats, an effect that was associated with increased CREB function and NPY production in the central and medial amygdala. And by administering compounds that promote CREB function and NPY production in the central amygdala, researchers were able to reduce anxiety — and alcohol intake — in P rats. On the other hand, by disrupting CREB function (and the concomitant NPY production) in the central amygdala of NP rats, the researchers were able to provoke anxiety-like behavior and promote alcohol intake in those animals.

Dr. Pandey and his colleagues proposed that decreased CREB-dependent NPY production in the central amygdala might be a pre-existing condition for anxiety and alcohol-drinking behaviors.

“Our findings implicate this pathway in genetic predisposition to high anxiety and alcohol-drinking behaviors of P rats,” says Dr. Pandey. “Future studies should explore the relationship of other CREB-related compounds to these phenomena in P rats or other animal models.”

The National Institute on Alcohol Abuse and Alcoholism, a component of the National Institutes of Health, U.S. Department of Health and Human Services, conducts and supports approximately 90 percent of the U.S. research on the causes, consequences, prevention, and treatment of alcohol abuse, alcoholism, and alcohol problems and disseminates research findings to general, professional, and academic audiences. Additional alcohol research information and publications are available at www.niaaa.nih.gov.



richardbenson
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08 Aug 2007, 6:05 pm

are rats similar to people though? ive always wonderd how a study on rats or mices for that matter would have the same effect on humans?


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Amarantha
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08 Aug 2007, 6:10 pm

I do this a bit. A drink or two can take the edge off my reticence and help me get involved in the conversation. And being a little drunk is a good excuse for anything odd in one's behaviour. I never get violent or embarrass myself. I do spend the next few days wondering if I said anything stupid, but then I do that anyway ;P The alcohol slightly increases the chance of saying something stupid, but only because I've said more things.

I used to get a kind of "foreign-accent syndrome" when I got really drunk. I'd start talking with a British accent, which would morph into Scottish and then Irish before shifting back to my usual Australian as I sobered up. The weird part was I never knew I was doing it until someone pointed it out, and even when I knew I had a hard time stopping. It hasn't happened for a while - I think I'm getting too old to get that drunk ;)

Edit - I can relate to the subject of being tired-drunk. Sometimes I'll start giggling at nothing, and that's when my boyfriend will say, "You're tired, aren't you?" And I'll just keep giggling :P



Last edited by Amarantha on 08 Aug 2007, 6:16 pm, edited 1 time in total.

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08 Aug 2007, 6:13 pm

richardbenson wrote:
are rats similar to people though? ive always wonderd how a study on rats or mices for that matter would have the same effect on humans?


I think the amygdala is a primitive brain feature shared by even reptiles that predate mammals by millions of years. Fear is not a complex human only process. Plus we evolved from the same source and have alot of common DNA.

This is the link to the study:

http://www.jci.org/cgi/content/full/115 ... type=HWCIT



woodsman25
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08 Aug 2007, 6:40 pm

ya, i know little about rats but mice and humans are very much alike, and are because of that the prefered animal to do testing on as they have the best relation to humans.


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Griff
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08 Aug 2007, 7:05 pm

I have a schizotypal friend who sometimes binges on hard liquor, specifically rhye whiskey. He's otherwise the most sober person I know, and he says that it's the only 'downer' he's ever gotten any enjoyment out of (including mary jane, which he hates). He also seems to have an affection for ephedrine, which worries me occassionally.



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08 Aug 2007, 9:37 pm

When i did go out, i would drink to get drunk as opposed to drinking for pleasure as this was the only way to deal with social situations. Back then i'd never even heard of Aspergers so i'd just assumed i was socially inept :lol: and the only way to get round that was drinking. The only trouble was when i got drunk i would turn in to this whole other, very catty person and behave exactly like those people i can't stand :? so i stopped drinking.

I don't think it's a coincidence that i stopped socalising when i stopped drinking. :(



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08 Aug 2007, 10:00 pm

i goto partys sometimes. i like to smoke weed more then drink alcohol. but weed is more anti-social. i had a few ppl i used to get high w/ who where cool, we just 'chilled' they call it. but the ppl i know now, are not like that. they always wanna talk and talk and talk, do bs, go places and do crap. i hate that.
when im drinking, i am more social, but i dont talk as clear. i mess up on a lot of words. and because of this ppl think i am way drunker then i am.
i guess if i worked on that, i could pull it off.

another thing that makes me more social is going to MMA. after working out, grappling, sparring, i feel different. working ur mussels makes them release some chem thats like a drug. and the fact ur fighting makes u enter like a dif state of mind. its awesome.



Cervantes
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09 Aug 2007, 1:11 am

I've started drinking socially in the last year or two, and I think there's several bonuses...

- most people around you are drunk, so they don't notice your oddities so much
- drinking alleviates social fear. At least for me. After several stiff ones I worry a lot less about talking to strangers.
- drinking provides a good excuse. "Sorry, I'm usually better at talking, but I've had a few too many". (I've said this 5 minutes after getting to the club. Lying sucks, but she was cute!)
- watching drunk people is a good learning lesson. People forget their little quirks when they're drunk, they boil down their social behavior to a more base level, and therefore it's easier to observe and learn what base behaviors work and which don't.



picklepuss
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09 Aug 2007, 7:45 pm

mmaestro- thanks for redirecting me. This is what I was looking for.



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09 Aug 2007, 9:18 pm

Works for me.


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RockoTDF
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10 Aug 2007, 9:57 am

Beenthere wrote:
Basically that used to be the only way I "could" socialize with some effectiveness.

It also had a downside as it was sometimes hard to moderate the safe levels...you had to know the level of alcohol that made you social...and the level of alcohol that turned you into an a$$ & the level of alcohol that made you stupid. That was were my problem was...distinguishing between those levels. :wink:


This is the same for anyone who drinks



Sylvius
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10 Aug 2007, 4:20 pm

I doubt I get better at socialising when I drink, but I am more willing to do it. And that makes it worth it.



blacktext
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11 Aug 2007, 3:24 am

You're still the same person regardless. People judge others on many different levels. Your drinking most likely has very little to do with any social success.