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Sophist
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04 Sep 2007, 4:54 pm

mmaestro wrote:
costre wrote:
Why need real physical brains?
I would think using MRI and/or EEG instead. Get samples from living thinking brains instead of dead ones. After all, it's what our brains are doing when we're alive that makes us autistics or not.

Sometimes what your brain is doing is dependant on the underlying physical characteristics. Sure, you can get a lot of that from modern scanning methods, but some things you only see when you take a slice and put it under a microscope. The thing is, you don't know how useful doing that is going to be 'til you actually have a decent selection of samples to look at. You may be right, it may be utterly useless. But no one will know 'til they have some to actually check, first. (And anyway, why object? You planning to use your brain after your death?)


Yes, my friend is currently doing some postmortem work on ASCs and there are telltale signs regarding the minicolumns (pyramidal cell columns in the brain). There are definite qualities to an autistic brain, although it takes a particular technique to view the density of those columns, the size, the neuropil space, etc.

Unfortunately, you can't study minicolumns on fMRIs or EEGs. (Hopefully one day, but as of now, no. :? )


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0_equals_true
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04 Sep 2007, 5:00 pm

I pretty much want to donate my whole body to science. But I've not thought about the individual causes. I would even know the best way to do it. Presumably I could just write it in my will.



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05 Sep 2007, 2:12 pm

0_equals_true wrote:
I pretty much want to donate my whole body to science. But I've not thought about the individual causes. I would even know the best way to do it. Presumably I could just write it in my will.


I'm not exactly certain what legalities are involved. But I will be meeting up with my friend in Kentucky in mid-October and we'll be discussing this and I can let you all know. I will ask him what is "standard". I'm fairly certain you'd need to let your family know because wills aren't often read until a good time after you're dead and there's really a very short time after death, usually only a few hours, to remove the brain before it decays so much that it's unusable. It's one of the fastest decaying organs and turns to jelly in under a day's time.


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TheMachine1
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05 Sep 2007, 2:25 pm

Sophist wrote:
0_equals_true wrote:
I pretty much want to donate my whole body to science. But I've not thought about the individual causes. I would even know the best way to do it. Presumably I could just write it in my will.


I'm not exactly certain what legalities are involved.


The law never stopped Frankenstein's research. For $1000 I can begin obtaining all the brains you needs........shovel in hand.



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05 Sep 2007, 4:41 pm

TheMachine1 wrote:
Sophist wrote:
0_equals_true wrote:
I pretty much want to donate my whole body to science. But I've not thought about the individual causes. I would even know the best way to do it. Presumably I could just write it in my will.


I'm not exactly certain what legalities are involved.


The law never stopped Frankenstein's research. For $1000 I can begin obtaining all the brains you needs........shovel in hand.


You'll need a pass and a key more likely... to get into the morgue. ;) Like I said, brains turn to unusable jelly pretty quickly.


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05 Sep 2007, 6:02 pm

Sophist wrote:
0_equals_true wrote:
I pretty much want to donate my whole body to science. But I've not thought about the individual causes. I would even know the best way to do it. Presumably I could just write it in my will.


I'm not exactly certain what legalities are involved. But I will be meeting up with my friend in Kentucky in mid-October and we'll be discussing this and I can let you all know. I will ask him what is "standard". I'm fairly certain you'd need to let your family know because wills aren't often read until a good time after you're dead and there's really a very short time after death, usually only a few hours, to remove the brain before it decays so much that it's unusable. It's one of the fastest decaying organs and turns to jelly in under a day's time.


basically... your body usually goes to universities and you cannot tell them how to use your body... they may just burn it cause they already have too many donations

you also cannot accept money for your body.... though there are handling fees "associated" with the process for the unis that somehow winds up in the donator's family's hands, usually.



dont forget to donate portions of your brain tumors when you have them biopsied or removed!


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0_equals_true
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05 Sep 2007, 6:17 pm

Sedaka wrote:
basically... your body usually goes to universities and you cannot tell them how to use your body... they may just burn it cause they already have too many donations

you also cannot accept money for your body.... though there are handling fees "associated" with the process for the unis that somehow winds up in the donator's family's hands, usually.



dont forget to donate portions of your brain tumors when you have them biopsied or removed!

Surely you could just write in the will that they don't get it if they aren't going to use it and instruct a lawyer to find a suitable university.

The money thing cracked me up :D



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06 Sep 2007, 8:54 am

0_equals_true wrote:
Sedaka wrote:
basically... your body usually goes to universities and you cannot tell them how to use your body... they may just burn it cause they already have too many donations

you also cannot accept money for your body.... though there are handling fees "associated" with the process for the unis that somehow winds up in the donator's family's hands, usually.



dont forget to donate portions of your brain tumors when you have them biopsied or removed!

Surely you could just write in the will that they don't get it if they aren't going to use it and instruct a lawyer to find a suitable university.

The money thing cracked me up :D


no, they are very serious about that kind of stuff.

i was thinking about this kind of stuff a while back... and still do... as i think it's very important to increase the interface between science and the autistic community.

but body donating does have a system already set up and there are restrictions with what you can do. i don't know how much waggle room there is but, i remember being discouraged by it.... for what i was hoping to accomplish via brain donations.

which is why im hoping fMRIs will take off and techniques for isolating brain activity will become refined... that way, you can analyze active autistic (and other) brains.


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06 Sep 2007, 12:30 pm

Sedaka, on a side note, I love that Lil' Bush quote. That's an awesome show. :D


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Deefor4
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06 Sep 2007, 2:40 pm

Well, you're very welcome to mine, if you can find it...

Will the fact that I haven't been professionally diagnosed as having Aspergers be a problem? And is it possible to freeze brains? Otherwise, by the time it gets to you from the UK, it's going to be dripping out of the Jiffy bag. (Apologies to those of you who are eating :oops: )



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07 Sep 2007, 2:29 pm

Deefor4 wrote:
Well, you're very welcome to mine, if you can find it...

Will the fact that I haven't been professionally diagnosed as having Aspergers be a problem? And is it possible to freeze brains? Otherwise, by the time it gets to you from the UK, it's going to be dripping out of the Jiffy bag. (Apologies to those of you who are eating :oops: )


It would have to be professionally preserved in the UK and then can easily be sent elsewhere, because once it's properly preserved in the formaldehyde it's good to go. :)

There's also the possibility of having an international brain bank so that it would be part of the same bank but a UK site, so your brain could possibly be used in UK research.


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07 Sep 2007, 2:45 pm

Sophist wrote:
You'll need a pass and a key more likely... to get into the morgue. ;) Like I said, brains turn to unusable jelly pretty quickly.


Any one need some cheap jars of jelly? :oops:



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07 Sep 2007, 3:10 pm

Sophist wrote:
Deefor4 wrote:
Well, you're very welcome to mine, if you can find it...

Will the fact that I haven't been professionally diagnosed as having Aspergers be a problem? And is it possible to freeze brains? Otherwise, by the time it gets to you from the UK, it's going to be dripping out of the Jiffy bag. (Apologies to those of you who are eating :oops: )


It would have to be professionally preserved in the UK and then can easily be sent elsewhere, because once it's properly preserved in the formaldehyde it's good to go. :)

There's also the possibility of having an international brain bank so that it would be part of the same bank but a UK site, so your brain could possibly be used in UK research.


OK, well, if any or all of these things are surmountable, it's all yours. I'd like to think I helped another Aspie somewhere in the future. :wink:



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07 Sep 2007, 3:30 pm

Cool beans. :)


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07 Sep 2007, 6:59 pm

Just got to remember not to blow my brains out, that wouldn't be an impressive submission. :? :wink:



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08 Sep 2007, 5:33 pm

Yes, we don't want to prompt any suicide submissions, please. Most likely by the time you'd be found, your brain would be goo. ;)


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