My husband John uses different hands for different things... basically it comes down to small motor skills versus gross motor. He writes with his left hand but uses his right hand for gross-motor things like using a hammer. He says that when he was a kid, his hands wouldn't move separately: they always made mirror-image movements, and if one crossed over the midpoint, he couldn't tell where it was anymore. (Maybe this has something to do with that article about how autistics have some difference involving the connection between the right and left halves of the brain?)
John and I are both diagnosed with Asperger's. I'm fully right-handed, but we're both left-right challenged when it comes to thinking about the directions. When someone says "Turn left," it takes us a moment to figure out which direction that is. Also, I never notice what hand someone is using unless I have some specific reason to look for it. I can know people for years and never notice whether they're right-or left-handed unless they mention it.
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Erika Hammerschmidt:
Author of "Born on the Wrong Planet," "Kea's Flight" and other books