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Heidi80
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14 May 2012, 5:22 am

My asperger's haven't worsed with age, but I'm more sensitive now and don't have to pretend to be normal



HalibutSandwich
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14 May 2012, 7:27 am

Apple_in_my_Eye wrote:
I've been looking up stuff on Google Scholar and it turns out that excessive stress hormones for too long damages the hippocampus, which is involved with memory. So, it makes sense that stress ==> memory problems. Studies done with people with PTSD (runaway stress reaction) and tumors that cause excessive secretion of stress hormones end up with the same impairment in verbal memory. So, were talking major stress levels here for that to happen (or else ASD folk have a lower threshold for such damage).

This is interesting (since I'm also having memory problems, age 42). But maybe it's not the hippocampus. Some research has shown people with autism have a less developed hippocampus. But newer research is showing something different. Maybe it's the amygdala:
Quote:
"There was a significant group difference in aging of left amygdala; controls, but not individuals with Asperger syndrome, had a significant age-related increase in volume (r = 0.486, P<0.01, and r = 0.007, P = 0.97, z = 1.995). There were no significant group differences in volume or age-related effects in hippocampus. Individuals with Asperger syndrome have significant differences from controls in bulk volume and aging of the amygdala."
- http://www.ncbi.nlm.nih.gov/pubmed/21948742

The amygdala is also involved in memory so that makes sense. What's more:
Quote:
"We found that amygdala volume correlates with the size and complexity of social networks in adult humans. An exploratory analysis of subcortical structures did not find strong evidence for similar relationships with any other structure, but there were associations between social network variables and cortical thickness in three cortical areas, two of them with amygdala connectivity. These findings indicate that the amygdala is important in social behavior."
- http://www.nature.com/neuro/journal/v14 ... .2724.html


Also, there's evidence the left amygdala is involved in the positive reinforcement mechanism of the brain. That might explain why many of us have such low self esteem and never feel like we're moving in the right direction. And why in my case no matter how much I'm rewarded and praised I still feel like a worthless piece of s**t that's just doing everything wrong. :roll:

Is modern research finally getting closer to understanding what causes Aspergers?


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Apple_in_my_Eye
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15 May 2012, 1:12 am

^ Very interesting stuff HS. I haven't even gotten to looking for ASD-specific stuff yet. I.e. I wonder what the brains of people w/ASD and PTSD (and also those dx'ed late in life?) look like.

I read somewhere that explicit memory is a hippocampal function whereas implicit memory is what the amygdala does. So, CRS syndrome would presumably be a hippocampal thing and feeling lost or directionless the amygdala thing (maybe).

That thing about social networks -- makes me think about how people remember who to fear and who not to fear (and who would be easy to take advantage of). I wonder if a smaller amygdala leads to ASD egalitarianism.



Ataraxis
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15 May 2012, 1:51 am

HalibutSandwich wrote:
Also, there's evidence the left amygdala is involved in the positive reinforcement mechanism of the brain. That might explain why many of us have such low self esteem and never feel like we're moving in the right direction. And why in my case no matter how much I'm rewarded and praised I still feel like a worthless piece of sh** that's just doing everything wrong. :roll:

Is modern research finally getting closer to understanding what causes Aspergers?


That sounds like me, I take compliments almost as badly as criticism. If I had a choice, people who were happy with something I'd done would just smile and do that single head nod thing that indicates respect or acceptance or something along those lines. I hate the squirming inside feeling I get if someone goes on in a positive way about something I've done, for some strange reason it always makes me feel inadequate, like I'm not worthy of it or stealing credit from someone else, even if no one else was involved.


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vanhalenkurtz
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15 May 2012, 4:11 am

The_Perfect_Storm wrote:
I'm significantly improving. Don't see that changing. Ever.


That is beautiful.

I believe better. Old(er) people receive less attention in society (unless they are authority figures) so there's less heat.


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SteelMaiden
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15 May 2012, 12:04 pm

I have got worse with age, but I think the stress of repeated psychotic episodes that started when I was 15 (I'm now 22 and have had over 20 quite florid psychotic episodes with incomplete remission in between) made my Asperger's get worse.


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cbeckmandc
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15 May 2012, 8:23 pm

I've read Tony Attwood. I believe he actually says Aspergers get better with age. That is why it is often difficult to diagnose as you get older. The reason is that we "figure out" how to fit into NT society. For example, although I have no innate understanding of social cues I can use my brain to figure out social cues that I've figured out in the past.



FishStickNick
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15 May 2012, 11:25 pm

I wouldn't say I've gotten worse than age. I've gotten better in some respects, but I will say that ever since I've gotten a real job, some of my weaknesses have become more apparent.



Onyxaxe
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08 Jun 2012, 2:21 am

There's no debating whether I got worse with age or nor. I was pretty NT as a child, just reserved. Now I have meltdowns, trouble getting my limbs to coordinate, mute spells, trouble in public due to noises and lights. Most symptoms aside from anxiety and ocd surfaced around 14 or 15, I'm 23 now and it's unbearable sometimes.



ozman
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18 Jun 2012, 9:56 pm

for me i was getting worse, probably because I thought I was in a healthy relationship, in reality I was really hurting my nt wife- I can now see that many ( but not all) of my aspie ways are not healthy, and I need to change/grow/evolve. Whether this saves my marriage is irrelevant, although it is a bonus if it does...



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18 Jun 2012, 10:24 pm

Not sure if its worse. But I don't have the mental energy as when I was a kid. My mind tires easly now. But also the older I get I seem to be stuck in life. I might be 28 but I'm still like 18 ish. It's weird to explain.

I won't be old and wise that's for sure. Just old and dumb lol. I still feel very much like the kid I was still am. I can still find my self doing odd stuff like playing with old toys from the basement storage



loner1984
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18 Jun 2012, 10:25 pm

Not sure if its worse. But I don't have the mental energy as when I was a kid. My mind tires easly now. But also the older I get I seem to be stuck in life. I might be 28 but I'm still like 18 ish. It's weird to explain.

I won't be old and wise that's for sure. Just old and dumb lol. I still feel very much like the kid I was still am. I can still find my self doing odd stuff like playing with old toys from the basement storage



auntblabby
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19 Jun 2012, 1:09 am

loner1984 wrote:
Not sure if its worse. But I don't have the mental energy as when I was a kid. My mind tires easly now. But also the older I get I seem to be stuck in life. I might be 28 but I'm still like 18 ish. It's weird to explain. I won't be old and wise that's for sure. Just old and dumb lol. I still feel very much like the kid I was still am. I can still find my self doing odd stuff like playing with old toys from the basement storage

welcome to our neat little cool 8) club, Loner :) nothing wrong with playing with one's fave toys :bounce: i am a big kid also. when you get to be my age, you will find things are the same, only more so. :hmph:



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19 Jun 2012, 1:46 am

you learn to hide the symptoms better. but you may get tired of people. i dont want to have anything to do with people anymore except my brother and his family, but in my early twenties i was actually interested in people, although not much.


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