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psych
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04 Dec 2006, 12:17 pm

Deutha wrote:
did u know...DMT..the illegal psychadelic drug....is what is secreted from ur pineal gland(3rd eye) at night to let u dream? so by dreaming u are using illegal drugs thereby supporting their use?


are you sure? I would have thought DMT wasnt the primary neurotransmitter involved in dreaming, otherwise we'd probably be dreaming of more exotic things like elves & pixies in cyberspace.



goomba
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04 Dec 2006, 12:59 pm

psych wrote:
Deutha wrote:
did u know...DMT..the illegal psychadelic drug....is what is secreted from ur pineal gland(3rd eye) at night to let u dream? so by dreaming u are using illegal drugs thereby supporting their use?


are you sure? I would have thought DMT wasnt the primary neurotransmitter involved in dreaming, otherwise we'd probably be dreaming of more exotic things like elves & pixies in cyberspace.

It's hypothesized that DMT is secreted from the pineal gland. Don't think it has actually been verified yet. I read once that DMT could be related to lucid dreaming, NDE, and hypnagogic or "spiritual/paranormal" experiences. Melatonin is related to the dreamstate as well. Our brains are fairly familiar with these neurotransmitters, and can be "processed" quite rapidly, say 30 seconds.
Revenant wrote:
Ingesting DMT is a waste. It will be broken down by the stomache acids before entering the bloodstream.

That's why you take an MAOI with it ie: Harmine/harmaline (tobacco, passion flower).



veridicus
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04 Dec 2006, 1:27 pm

DMT is orally active if taken with a reversible MAO inhibitor. This is the basis of the hallucinatory drink Ayahuasca.
There is nothing intrinsically wrong with intentionally altering one's consciousness. It's endemic to all cultures of the world and many species besides homo sapiens make a practice of it.


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04 Dec 2006, 4:19 pm

Quote:
That's why you take an MAOI with it ie: Harmine/harmaline (tobacco, passion flower).


Monoamide Oxidase-Inhibitors are extremely dangerous to take with drugs that increase serotonin levels in the brain. Particulary psychedelics and amphetamines such as DMT, LSD, LSA, 5-Meo, MDMA and others. MAOIs inhibit destruction of serotonin. So the brain would be over-flooded with serotonin which cause desentisizing of receptors.

I think www.dancesafe.net(If i remember correctly) had an animation of the brain under the influence of MDMA. You should check it out. It is relevant to all drugs that release serotonin in large amounts.

Now I know Ayahuasca brews contain MAOIS as well as other interesting psychoactives. When I was a tripper, I always wanted to try Ayahuasca after seeing the movie "Blueberry"(If I remember the title correctly. I was kind of disabled mentally that time from all the drugs). It was about this cowboy dude who drank ayahuasca. There was a nice rendering of his psychaedelic experience.
I've forgotten the plot since this was over 2 years ago, and I was pretty sedated all the time back then.



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04 Dec 2006, 5:15 pm

"Coffee is clearly a drug by any reasonable definition. It's purely through an accident of history which drugs are legal."

Health Canada stated caffiene was more addicting then pot. I cant remember that actual categories but Marijuana was only worse then Caffiene in one category which was the 'actual high' you received from it..



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04 Dec 2006, 5:41 pm

Coffee acts by stimulating the adrenal glands to secrete epinephrine, the stress neurohormone. Add a small quantity of dopamine and serotonin and you have the formula for the caffeine high.
Epinephrine is in the adrenaline-family and increases heart beat and alertness. Chronic Caffeine abuse cause the N-methyl transferase gene-expression disorder which may be a semi-permanent disorder.

This does not mean one cannot enjoy Caffeine, but in large doses and in frequent administration it can cause some bad side effects.



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04 Dec 2006, 5:45 pm

Everything can.. eating carrots everyday can make your skin turn orange

Studies show drinking coffee can help you, others say no

Black burnt things on meat causes cancer but so does the sun and microwaving something with plastic wrap over it

The point is, everything simply comes down to moderation.. Dont suck on a pipe with all day you'll be fine.. after all, as long as you ARE happy and not just on some massive drug trip, who cares? I dont consider pot to be anywhere close enough to take you on a 'trip' minus the first time you use it..



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04 Dec 2006, 9:38 pm

Revenant wrote:
Quote:
That's why you take an MAOI with it ie: Harmine/harmaline (tobacco, passion flower).


Monoamide Oxidase-Inhibitors are extremely dangerous to take with drugs that increase serotonin levels in the brain. Particulary psychedelics and amphetamines such as DMT, LSD, LSA, 5-Meo, MDMA and others. MAOIs inhibit destruction of serotonin. So the brain would be over-flooded with serotonin which cause desentisizing of receptors.

I think www.dancesafe.net(If i remember correctly) had an animation of the brain under the influence of MDMA. You should check it out. It is relevant to all drugs that release serotonin in large amounts.

Now I know Ayahuasca brews contain MAOIS as well as other interesting psychoactives. When I was a tripper, I always wanted to try Ayahuasca after seeing the movie "Blueberry"(If I remember the title correctly. I was kind of disabled mentally that time from all the drugs). It was about this cowboy dude who drank ayahuasca. There was a nice rendering of his psychaedelic experience.
I've forgotten the plot since this was over 2 years ago, and I was pretty sedated all the time back then.

The potential dangers of MAOI anti-depressants kept me away from them. There are a ton of dietary requirements (basically, avoiding foods with tyramine content - that is, fermented, aged, or overripe foods ie: cheese). Never take an MAOI drug with the SSRI anti-depressant type or MDMA, as this can lead to Serotonin Syndrome (as you say, the brain would be over-flooded with serotonin) causing various adverse effects, even death.

Reversible MAOI (such as harmala alkaloids) use is less cause for concern when combined with a tryptamine hallucinogen, but one should still be cautious of all seritonergic drugs, or drugs acting on 5HT2 receptor when combined with an MAOI. And never combine an MAOI with SSRI or amphetamine drug. As for tryptamine (psilocybin, DMT) be careful, know what foods to avoid "just in case", ensure the MAOI is reversible in effect (and short acting, 6-12 hours at most). Know the drug, dose, and so on. Basically, do your research; stay safe.

The url for Dancesafe is Dancesafe.org.



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05 Dec 2006, 4:24 am

Quote:
The potential dangers of MAOI anti-depressants kept me away from them. There are a ton of dietary requirements (basically, avoiding foods with tyramine content - that is, fermented, aged, or overripe foods ie: cheese). Never take an MAOI drug with the SSRI anti-depressant type or MDMA, as this can lead to Serotonin Syndrome (as you say, the brain would be over-flooded with serotonin) causing various adverse effects, even death.


Yep, this guides me away from MAOIs. Unfortunately, I was forced to administer SSRIs when i was hospitalized 3 years ago. At that time, I knew nothing about drugs and medicines and thought "Well, if they say it works it probably does".

Another interesting thing is that SSRI's can help fight MDMA addiction(mental addiction) since it blocks the reuptake mechanism.


Quote:
The url for Dancesafe is Dancesafe.org.


Thanks for the correction :wink:



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05 Dec 2006, 11:51 am

:twisted:

http://www.npr.org/templates/story/story.php?storyId=6376594


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08 Dec 2006, 10:45 pm

The UK government recently commissioned a study and produced a scale of how harmful each one was socially and medically. The evidence speaks for itself. Prohibition doesn't work.

Image

GLOSSARY
Benzodiazepines: Wide-ranging class of prescription tranquilisers
Buprenorphine: Opioid drug used in treatment of opiate addiction
4-MTA: Amphetamine derivative sold as 'flatliners' and ecstasy
Methylphenidate: Amphetamine-like drug used to treat ADHD
Alkyl nitrites: Stimulant often called amyl nitrites or 'poppers'

NOTICE the presence of two Class A drugs - ecstasy and LSD - in the bottom six.
This places them well below tobacco and alcohol and a number of class B and C drugs

Alcohol is just as much a drug as anything else. It is simply the path of history why some drugs like caffeine and tobacco are legal, but others are not.



troymclure
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09 Dec 2006, 1:46 am

I'm an ex-raver and that graph looks pretty right. Makes sense when I stop and think about it even.

MDMA is a great social disinhibitor, people tend to be much more open and as a result i understood things better (always had problems with speaking too literally). Also the constant beat is kinda soothing at a rave, not too mention the fact that you are expected to do nothing but stim the whole time.

Well, if you think dancing is a sort of stimming that is. First thing i do at a rave is buy a pair of glowsticks then spend the rest of the night making pretty patterns of light with my hands and trip out on it. I'm not even sure if stimming is the right term, it's more a senses thing, you can get lost in the light and the movement, it's like you can tune out the outside world but thing is, everyone else is doing it, you can look around and feel like you're a part of a crowd. That's what early raves where based on. PLUR was the slogan of the 90's rave movement. Peace. Love. Unity. Respect.

Peace kids. :P



Deutha
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10 Dec 2006, 12:34 pm

imagine being a guinea pig at those trials...u'd be all over the shop after finishing with that lot :P

seriously tho...that makes me more pissed off pot isn't legal! i just wanna be able to go buy it from a shop sheesh...

(NB.. i know what ur thinking...move to amsterdam then....well i've been there and tis a fabulous city...but the street names are freakin crazy! ...and the truth is i can't be stuffed learning the language :oops: (which i'd prolly hafta do if i intended to live/work there etc))



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10 Dec 2006, 12:44 pm

Deutha wrote:
imagine being a guinea pig at those trials...u'd be all over the shop after finishing with that lot :P

seriously tho...that makes me more pissed off pot isn't legal! i just wanna be able to go buy it from a shop sheesh...

(NB.. i know what ur thinking...move to amsterdam then....well i've been there and tis a fabulous city...but the street names are freakin crazy! ...and the truth is i can't be stuffed learning the language :oops: (which i'd prolly hafta do if i intended to live/work there etc))


The leaf promotes peace and 'the government doesnt want that' 8)



Seigneur
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10 Dec 2006, 1:00 pm

I'd use marijauna, hash or LSD if I had them. Alcohol, maybe. Tabacco and other drugs, no.

Of course I don't have those drugs, and I've never used them. Meh.



Panik
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10 Dec 2006, 1:12 pm

Uhm i've smoked hash mostly and used shrooms a couple of times. Was probably a bad decision to start using psychedelic drugs at a young age, I was too inexperienced. I'd still say yes to pot though, find it very relaxing :P