It seems that many persons understand each other even when they are using many pronouns in their speech. They seem to "guess" what the other person means.
For me, each pronoun is a difficult one, unless they have been preceded by a noun I can connect the pronoun to.
If someone starts talking to me, using pronouns, I have to put each pronoun to "a shelf" in my mind, in order to later clarify their meaning. If all the "shelves" get full (I guess the working memory overflows), I just have to stop them and tell that I was not "on the map" and ask them to clarify what they were talking about.
It is easier for me in formal meetings, because there I can write notes. Then I can ask questions based on the notes, and actually people seem to like it. I appear to them as being interested in their subject, and they are glad to clarify.
In informal discussions, however, I find people getting frustrated towards me, after they have been talking for a while only to find out I have not had a clue what they were talking about.