DS has the Focalin, and so far so good. No reaction right now. The dosage is 10 mg. to start. If he doesn't see a benefit, dr. will up the dosage. I have been concerned that he would have an adverse reaction, since doing much research on Focalin on the internet. I'm becoming afraid that my son doesn't respond to any of these medicines without having dosages that would be over the limit. Oh well . . .