Is it likely for AS to "skip" a generation?

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So, I suspect I have AS and I also think my grandfather has it.

However, I'm very sure my father doesn't have it and I don't think my uncle or my aunts have it.

Is it likely for the AS gene to "skip" a generation?

I am also sure that my grandfather had it, because we share alot of personality traits and mental quirks. I am reasonably sure that my mother has it, too. Maybe it does, but at least judging from my perspective, it could also not.

I don't know... I know of at least one gene that gets passed on but can lay dormant for generations.

Most of my family has some sort of mental issue or another...most of them are in denial about it, but yeah as far as I know I am the only one with aspergers.

Yes, it can.

AS is not caused by a single gene, and it's not caused by the same combination of genes every time. That means there are many different ways for AS to happen. Your grandfather might have had genes A, B, C, and D, and passed on A and B to your dad. A and B weren't enough to cause AS all by themselves, but when your dad passed on A and B to you, and your mom passed on E and F (also not enough to cause AS by themselves), your A, B, E, F combination was enough to cause AS.

It's simplistic but that's the general way it tends to happen.

Genetics are a funny thing you never know what you will get. I had a cousin who swore up and down the child he had was not his because the kid had jet black hair and almond shaped eyes. The kid looked half asian. Everyone in his wife's family have sandy brown hair the same with my family with the exception of one aunt and an uncle who had black hair. But our family has a lot of native American ancestory a few generations back. After a paternatity test the kid was his.

The autism gene could skip a generation but it will always lurking in the background ready to pop up somewhere down the line. Two generations from now your great grandchild could have a kid with autism and wonder how they got since no one in their family has it. They never have met you so how would they know it is in their family blood.

It could skip a generation or someone may just have alot of autistic traits without being fully autistic. Supposedly everyone has a touch of autism in them.

Thanks for all the posts!

In our situation, it has most definitely skipped a generation.

When my husband and I married, we were the perfect storm as far as Asperger's. Both of our fathers would have most definitely been diagnosed, and then our oldest son would have been diagnosed (he was born the same year the diagnosis was made official, but no doctor ever caught on to it with my son), and our youngest son WAS diagnosed.