According to a quoted text that I found at http://www.wrongplanet.net/postp4252020.html#4252020,
Quote:
In order to test the hypothesis that acute schizophrenia episodes have a negative impact on cognitive function, 35 consecutive non-abuse schizophrenia outpatients (age < 60) were enrolled in this study. All subjects for whom grades from the 9(th) year of the Swedish school system were available, had to complete a comprehensive computerized neuropsychological test session. Symptoms were rated by PANSS and GAF, previous episodes were tallied, and medication was logged. A premorbid cognitive score was calculated on the basis of school grades and validated by comparison with academic career and current cognitive performance (r = 0.56). Half had college level studies or higher, and the overall school grades for the group were above average. PANSS (sum = 59) and GAF [59] ratings as well as medication (M = 230 CPZ units) suggested a moderate symptom level. Two patients had no neuroleptic drugs, 16 had atypical and 17 had conventional neuroleptics. Vocabulary was intact. On average, patients had lost 1 standard deviation (SD) in most cognitive tests but response time slowing amounted to 3.5 SD.There were no differences in cognition between drug types and no correlation with CPZ dose. The number of previous episodes was positively correlated with reaction time prolongation and negatively correlated with short-term verbal memory, consistent with a previous study suggesting that acute episodes cause specific cognitive reduction.
It appears that a significantly reduced response time is suggestive of schizophrenia. How exactly are "response times" measured?
I'm curious because this seems to be a really good way of detecting schizophrenia, in conjunction with other diagnostic tools that rule out other possible conditions that affect response timing (Like possibly ADHD and autism), since a reduction of 3.5 SD should be easily detectable even if one was originally gifted in "response times". Even if one didn't know what their response times were before the possible development of schizophrenia, a response time 1.5 SD below the average would definitely implicate it, especially if they did or do well on other measures that are highly correlated with 'response times'. Like, maybe, some subtest on the WAIS like the 'processing speed' subtests (Like encoding?)?
Does anyone know if response times are affected in ADHD? How about Autism?
I'd imagine so based on stereotypes. But, I kind of get the impression that many people with autism seem to be fairly quick at responding to other people judging from my experiences on the Wrong Planet chatroom, so maybe not so with autism.
ADHD would probably be affected in response times. Or maybe not.
ADHD response time research
http://www.sciencedirect.com/science/ar ... 1800000196 - It appears that one can diagnose ADHD based on the response time, though this paper doesn't seem to tell you the mean response times for the ADHD test subjects.
http://www.livestrong.com/article/45537 ... -caffeine/ - this site claims a slowed response time.
http://www.sciencedirect.com/science/ar ... 9810001601 - research article claims a slowed response time but doesn't mention specifics, like what percentile the response times might be at in the general population. You have to pay to get the article... why must I pay to research and potentially help out humanity?
Autism response time research
http://www.ncbi.nlm.nih.gov/pubmed/9638 ... t=Abstract - claims a significantly slowed reaction time among those with autism with flashing lights.
Last edited by swbluto on 18 Dec 2011, 6:04 am, edited 5 times in total.