Noopept/Piracetam to treat NVLD/Asperger's?

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Has anyone tried any of the nootropic drugs, the most potent of which is noopept, for this purpose? They are legal to buy in the U.S. but not approved by the FDA.

Links

http://www.noopept.co.uk/

http://en.wikipedia.org/wiki/Noopept

http://link.springer.com/article/10.102 ... rue#page-1 (a study on rats)

Treating brain damage, including spatial memory, in Alzheimer's patients: http://jop.sagepub.com/content/21/6/611.short

Treating mild cognitive impairment: http://link.springer.com/article/10.100 ... -x?LI=true

A similar, but apparently more widely used (though weaker) drug is Piracetam: http://en.wikipedia.org/wiki/Piracetam# ... _and_usage

Used to successfully mitigate autism (need Ebscohost prescription):

Akhondzadeh, S., et al. A double-blind placebo controlled trial of piracetam added to risperidone in patients with autistic disorder. Child Psychiatry and Human Development, Vol 39(3), Sep, 2008. pp. 237–245.

Another study with piracetam treating cognitive impairment: http://www.ncbi.nlm.nih.gov/pubmed/18988050

Last edited by Tyri0n on 12 Feb 2013, 10:57 pm, edited 1 time in total.

i have been taking piracetam for impaired working memory/executive function for about 6 years. it is a miracle for me. i would probably be living in a group home if not for this drug. i also use nicotine gum (1mg 4-5 times a day) for a boost to working memory (or whatever... it is hard to put a label to what is improving, but i am clearly more functional with these drugs). without piracetam i cannot communicate effectively at all, my comprehension of speech and body language is more limited, i cannot read facial expressions, have absolutely no sense of what is going on with other people, and compeletely lack the capacity for a sense of familiarity (even with my own family. they are like strangers). some people take it and do not notice any effect, whereas the effect for me is profound both subjectively and to those who know me (including my doctor (she has recommended it to a number of patients with dysexecutive syndrome or similar issues and says they seem to benefit from it)).

that other racetams are more potent does not mean they are better or more effective. i have also tried aniracetam and experienced more side effects (with piracetam, at the dose i am taking 1700mg tid, there are no notable side effects (at higher doses, nervousness and psychosomatic pain)). i had difficulty sleeping when i took aniracetam even when i only took it in the morning. i can take piracetam immediately before going to bed and still fall asleep easily. i have thought about trying the others to see if any really are more effective (and not merely more expensive) than piracetam. if you are going to try racetams, try piracetam first. if you do not notice any improvement with piracetam (for me the effect begins less than 1/2 hour after taking it) then you probably do not have the right kind of problem for that kind of drug.

Different people on the spectrum react to different drugs and side effects, when they happen, can do serious damage, including killing you - my partner had a half dose of codeine, one of the safest and best understood drugs, and was totally paralysed for 16 hours, a full dose would have killed him. Some of the drugs you are talking about are extremely potent and could be dangerous.

Please do not experiment without talking to a doctor

The only time I've been seriously hurt was when a doctor prescribed SSRI's, and I almost killed myself. Doctors don't prescribe nootropics in the U.S. They are sold OTC as supplements. Piracetam is perfectly safe and had no side effects in clinical trials (and has been around for 4 decades), so I may try that one first.

I'm very curious about noopept, though, and wonder if anyone else has taken it because it seems better at repairing damage, as opposed to just providing a mental boost.

They all repair mental damage, just in varying amounts. There's also phenylpiracetam, which is so awesome it's on the WADA banned list.

Whenever I try serotonin raising supps I always get mentally worse. I wonder if many AS peeps have similar problems with serotonin raising agents.

does anybody know what possible cumulative effects these nootropic drugs have on the aging brain? like if a person started taking them regularly in their 20s, what condition might they end up in by their 60s?

i wondered that same thing about SSRI's. i know a couple of people who took them for 20+ years, and their memories are SHOT (might not be related, but i don't really know). studies don't really have to be long-long-term for a medicine to be approved by the FDA etc.

would a prudent person risk taking nootropics not knowing the long-term effects?

i wouldn't risk it, myself.

Absolutely no way that a medication could fix the abnormal brain circuitry of my NVLD brain. I'll gladly keep my deficits than try some extremely suspect medication.

Piracetam's been in use since the 60s. The newer stronger ones, less, but yeah.

Personally I hate NVLD as it makes driving hard.

there is no known risk in taking piracetam (after 40 years on the market). the substance is as close to utterly harmless as any medicine gets. it is about as risky as a morning cup of tea, perhaps less. whereas, not trying it, one may live the rest of one's life struggling needlessly with a problem that is treatable. for anyone already using adderal, ritalin, modafinil, or any other prescribed psychostimulant, this is worth trying as a safer alternative. it may be less effective in some ways, more in others, but with fewer side effects one might decide it is a worthwhile trade-off (as i did, switching from ritalin to piracetam). anyone with executive function disorder should try this medicine in the interest of their long-term welfare and happiness, in my opinion. i suppose it is not a bad idea to take it with guidance of a doctor, if one is so inclined.

If these drugs do, indeed, repair long-term damage, I would imagine there would be no need to take them long-term.

It could be the AS version of viagra for socializing though.

Take one pill 3 days before socializing efforts are scheduled... you have a 48hr period of 'normalness'.

and if your NT lasts longer than 48 hours be sure to consult a doctor.