I went through a period in my life from about age 17 to age 22 when I felt as if my autism 'flared up', so to speak.
I was struggling with a number of independence issues, combined with general confusion about how to properly approach other people on a social level. Then, when I got my first job, I initially felt good, because I got along reasonably with my co-workers and was learning new skills. However, fairly soon, I encountered more problems in the area of social interaction. I did not have any friends, didn't even have acquaintances for that matter, and I felt generally unhappy and inadequate.
I was surprised that this happened at all, especially because I had previously felt that I had all but 'conquered' my autism in my late teens. But after going through a dark, apathetic period, I began focusing on things in my personal life that I enjoyed doing and gave me a sense of fulfillment. I decided to give my 'me-time' some more priority during my off-work hours, so that I could feel better about myself, in spite of my failures in socialisation at that time. I realized that that was simply not my strong suit, and that I wasn't required to be a social butterfly in order to feel happy. Yes, I continued to practice my social skills and learn with every interaction I made, but I didn't try to live up to a standard I might not reach on short term.
I've mostly stabilized at this point, though I realize full well that there is no such thing as clear sailing all the way up until your final breath. There's gonna be struggle in the future, though I hope not much of it will have to do with my autism. I now feel that I have most of it under control, but there's still room for improvement.
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clarity of thought before rashness of action