Childhood disintegrative disorder - how long regression?

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Tilda
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05 Aug 2014, 12:37 pm

I'm just curious: how long period of time can a child with CDD regress? Like, several weeks, several months, or several years?



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05 Aug 2014, 12:44 pm

from what remember,people with CDD can start regressing at around four years of age up to before twelve years old though most regress much earlier but people with CDD are very low functioning in presentation.


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Tilda
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05 Aug 2014, 1:01 pm

KingdomOfRats wrote:
from what remember,people with CDD can start regressing at around four years of age up to before twelve years old though most regress much earlier but people with CDD are very low functioning in presentation.


Thank you for your reply. But I actually meant how long time they can regress when they have started to regress. :)



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05 Aug 2014, 1:54 pm

Temple Grandin writes in "Thinking in pictures" that children with disintegrative disorder regress between the ages two (or even earlier like 18 month) and seven and as KOR writes present mostly as very low functioning, but I don't know how long regress takes.
I regressed myself from age two but doubt having disintegrative disorder as I did not have fully developped speech at age two but echolalic speech to begin with and I am high-functioning, I think regress was more from environmental influences.
I just wonder, why Temple Grandin distincts between Kanner-type autistics and low functioning autistics? Does having Kanner-type autism exclude being low functioning? <--- sorry, off-topic questions.


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05 Aug 2014, 2:03 pm

Kanner autism is synonymous with "classic" autism, I believe. You could be "high-functioning" when you have classical/"Kanner" autism. It's based on the children which Kanner wrote about in 1943.



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05 Aug 2014, 2:17 pm

kraftiekortie wrote:
Kanner autism is synonymous with "classic" autism, I believe. You could be "high-functioning" when you have classical/"Kanner" autism. It's based on the children which Kanner wrote about in 1943.

This is what I thought as well, but in the book Grandin lists Aspergers Syndrom, PDD, Kanner-type autism and low functioning autism, for example "The exact timing of the sensory processing problems may determine whether a child has Kanner's syndrome or is a nonverbal low-functioning autistic". (p.39).
To me it reads as Kanner autism is distincted from low-functioning autism, but maybe I misunderstand it.


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05 Aug 2014, 3:34 pm

Eloa wrote:
kraftiekortie wrote:
Kanner autism is synonymous with "classic" autism, I believe. You could be "high-functioning" when you have classical/"Kanner" autism. It's based on the children which Kanner wrote about in 1943.

This is what I thought as well, but in the book Grandin lists Aspergers Syndrom, PDD, Kanner-type autism and low functioning autism, for example "The exact timing of the sensory processing problems may determine whether a child has Kanner's syndrome or is a nonverbal low-functioning autistic". (p.39).
To me it reads as Kanner autism is distincted from low-functioning autism, but maybe I misunderstand it.


I read it the same way. It's odd because most people hold the opposite view and think of Kanner-type autism as whatever their definition of LFA is.

If you'd like to judge for yourself whether Kanner's original patients would be LFA or HFA ....

Kanner's original paper from 1943: Autistic Disturbances of Affective Contact.

Kanner's follow-up paper from 1971: Follow-Up Study of Eleven Autistic Children Originally Reported in 1943


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05 Aug 2014, 3:55 pm

Tilda wrote:
KingdomOfRats wrote:
from what remember,people with CDD can start regressing at around four years of age up to before twelve years old though most regress much earlier but people with CDD are very low functioning in presentation.


Thank you for your reply. But I actually meant how long time they can regress when they have started to regress. :)


Seems it varies.

From Mayo Clinic page about CDD:

Quote:
Loss of developmental milestones may occur abruptly over the course of days to weeks or gradually over an extended period of time.


From www.patient.co.uk page about CDD:

Quote:
Loss of skills often reaches a plateau by around age 10. There may be some, very limited improvement, but this is seen in a minority of cases.


From Kaplan & Sadock's Concise Textbook of Clinical Psychiatry, 2011 ed. (pg 1201):

Quote:
The course of childhood disintegrative disorder is variable, with a plateau reached in most cases, a progressive deteriorating course in rare cases, and some improvement in occasional cases to the point of regaining the ability to speak in sentences.


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kraftiekortie
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05 Aug 2014, 5:08 pm

I should have clarified myself: "classic autism" could be "high-functioning," or "low functioning," I believe



GoldTails95
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30 Apr 2015, 11:12 am

I had something very similar when I was 2. And the between the time I regressed and the time I acquired language and improved (around 5 or 6 years when I started speaking again), I seemed to also fit the DSMIV criteria for CDD. But I did not. The reason for this is that it stays like someone like Harley Sheffield and the skills lost are lost for good. I gained back skills and made obvious improvement before my 10th birthday. Today I am similar to someone with Aspergers.
As for how long the CDD regresion takes, I say it depends on what type of separate progressive degenerative condition they have because many cases of CDD are caused by an accompanying progressive condition, like Rett Syndrome, TSC, Mitochondria Disease, delayed onset of symptons of Severe Anoxic Brain Injury (ie from near drowning),or Juvenile Onset Tay Sachs Disease. For those who heard about Tay Sachs Disease, you heard that it happens in Jewish babies. Well, there are atypical forms of Tay Sachs that onset at a later age and also happens in French Canadians along the St Lawrnce River, Amish, Irish,and Louisiana countryside Cajuns. For example, according to the Tay Sachs Foundation, a 2 year old who starts symptoms would detrioate faster and more severe than a 5 year old who started the symptoms. Because Juvenile Onset Tay Sahcs is considered a degenerative disease of the CNS and CDD has abnormalities in the CNS, CDD can be caused by Juvenile Onset Tay Sachs. Juvenille Onset Tay Sachs has the same age of onset range as Childhood Disintegrative Disorder, which is ages 2 to 10.As for the time it takes to regress, a 2 year old who gets Tay Sachs will regress to CDD faster than a 6 year old with Tay Sachs and CDD. With that being said, a 2 year old with Tay Sachs will regress to CDD in a 3 weeks while a 6 year old with Tay Sachs will regress to CDD in 10 months.


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GoldTails95
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25 Jul 2015, 7:36 pm

KingdomOfRats wrote:
from what remember,people with CDD can start regressing at around four years of age up to before twelve years old though most regress much earlier but people with CDD are very low functioning in presentation.

KingdomofRats, The age range of CDD is 2 to 10 not 4 to 12.And sometimes a rare nuerodegenerative disease, such as early onset Lafora disease is involved in the process.Even tough some of those mentioned nuerodegenerative disorders, early onset Lafora,have absolutely nothing to do with autism, that does not mean that it can co-exist in a kid with CDD and here is why:
Quote:
Wikipedia says:
In a later study, Lafora disease has been and is now viewed as a neurodegenerative disease, since prior to the actual formation of Lafora bodies there has been seen to be an impairment in the development of cerebral cortical neurons.

Another reason why it is possible for a kid to have both CDD and early onset Lafora:
Quote:
Textbook of Autism Spectrum Disorders says:
Although CDD is distinct from a nuerodegenerative disease in it's course and symptoms, these two disorders are not mutually exclusive according to the DSM-IV-TR, and a clinician should consider the possibility of a comorbid nuerodegenerative disease when examining a possible CDD case, especially one of late onset {Corbett et al 1977}

Age of onset range for Lafora is 8-18, while CDD, as I said and corrected, the age of onset range is 2-10.Both disorders have age of onset range overlaps at age 8-10, so misdiagnosis and possible comorbidity between the two disorders is possible. The same is true for some other nuerodegenerative diseases, tough a lot of them, including Lafora and juvenile onset Tay Sachs, have nothing to do with autism. By the way, the age of onset range for juvenile onset Tay Sachs is 2-10, same age of onset range as CDD, but again, if a comorbidity were to exist, it would be at a later age.


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