Thanks. The publisher provides a bit more context information at http://media.jamanetwork.com/news-item/ ... -uk-twins/.
Quote:
Beata Tick, M.Sc., of King’s College London, and coauthors examined genetic and environmental factors for risk of ASD and related traits from a population-based sample of all the twin pairs born in England and Wales from 1994 through 1996. The twins were assessed using several screening instruments: the Childhood Autism Spectrum Test (6,423 pairs), the Development and Well-being Assessment (359 pairs), the Autism Diagnostic Observation Schedule (203 pairs), the Autism Diagnostic Interview-Revised (205 pairs), and a best-estimate diagnosis (207 pairs). The study included twins with high subclinical levels of autism traits and low-risk twins, as well as those diagnosed with ASD.
The authors found that on all ASD measures, associations among monozygotic (identical) twins were higher than those for dizygotic (fraternal) twins, resulting in heritability estimates of 56 percent to 95 percent. The analyses highlight the importance of genetic factors in the cause of ASD along with moderate nonshared (different experiences among children in the same families) environmental influences, according to the study.
“We conclude that liability to ASD and a more broadly defined high-level autism trait phenotype in U.K. twins 8 years or older derives from substantial genetic and moderate nonshared environmental influences,” the study concludes.
This kind of research is very useful. Ironically it could lead to a realisation that people with certain genetic makeup thrive best in physical and social environments that minimise the risk of sensory overload and autistic burnout.
08 Mar 2015, 1:33 pm
