I know someone testing this hypothesis as you speak.
My ASD ex and I opened a retail business in a smallish-town city in Canada just over a year ago now. Note the past tense.
When the business opened, and before that, I was gungho and able to help out a lot in setting it up and then, running it. I spent more than 40hrs/week at that store, one of my 'normal' times that never last. It was only up and running 2 months though, before my ex and I had our first 'break-up' that lasted a few days. 6 months ago was another break-up and he ran the store for about a month with only the 1 kinda bumbling employee. After that month or 2, we slowly got back together again and I once again started taking regular shifts at the store, although with him being aware of my disabilities. Maybe a week ago we broke again and he's now, in christmas season, working 12, 14 hour days.
One of the reasons, however, where I think the relationship had an issue was me needing a lot of affection, and with him and I working so much, and me breaking down, and him needing so much downtime/alone time, he kept feeling pressured by me. This is all to say that I think he can't work and have a relationship, and I, of course, want him to choose a relationship over self-earning income, but I'm not sure he even agrees with the work/relationship balance thing I say anyways.
So far the business is doing well. So far my ex still seems like he's holding back a shutdown or a meltdown regularly though, multiple times a week.
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Not autistic, I think
Prone to depression
Have celiac disease
Poor motivation