Are atypical neuroleptics useful for ........

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Themis
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19 Oct 2007, 2:37 am

Are atypical neuroleptics useful for the reducing of repetitive behaviour in Asperger disorder in adolescents?The pshychanalysis or homeopathy are usefull mesures for Asperger disorder in adolescents?



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19 Oct 2007, 6:10 pm

No, antipsychotics haven't been shown to reduce stereotypical behaviour, afaik, but have been used to reduce irritability, anxiousnous and aggression - as usual to reduce symptoms rather then causes. Psychoanalysis appears less useful in AS, according to Attwood, symbols and meanings may be rather different then with NT's. Homeopathy hasn't been shown to effective with anything.



geek
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19 Oct 2007, 6:50 pm

If by repetitive behavior you mean things like stims (rather than obsessing over a favorite subject), there isn't much. I did read something recently which seems worth a try, though.

Quote:
Biol Psychiatry. 2007 Feb 15;61(4):551-3. Epub 2006 Aug 22.
Omega-3 fatty acids supplementation in children with autism: a double-blind randomized, placebo-controlled pilot study.
Amminger GP, Berger GE, Schäfer MR, Klier C, Friedrich MH, Feucht M.

Department of Child and Adolescent Neuropsychiatry, Medical University of Vienna, Vienna, Austria. [email protected]

BACKGROUND: There is increasing evidence that fatty acid deficiencies or imbalances may contribute to childhood neurodevelopmental disorders. METHODS: We conducted a randomized, double-blind, placebo-controlled 6-week pilot trial investigating the effects of 1.5 g/d of omega-3 fatty acids (.84 g/d eicosapentaenoic acid, .7 g/d docosahexaenoic acid) supplementation in 13 children (aged 5 to 17 years) with autistic disorders accompanied by severe tantrums, aggression, or self-injurious behavior. The outcome measure was the Aberrant Behavior Checklist (ABC) at 6 weeks. RESULTS: We observed an advantage of omega-3 fatty acids compared with placebo for hyperactivity and stereotypy, each with a large effect size. Repeated-measures ANOVA indicated a trend toward superiority of omega-3 fatty acids over placebo for hyperactivity. No clinically relevant adverse effects were elicited in either group. CONCLUSIONS: The results of this study provide preliminary evidence that omega-3 fatty acids may be an effective treatment for children with autism.

PMID: 16920077


A few things to note about this study:
(1) This is still a fairly isolated study, no guarantee it's reliable. Could have been funded by the fishing industry for all I know.
(2) Those are large doses of fish oil (five or six 1-gram capsules a day, if you take it the normal way), so a capsule a day won't cut it.
(3) Note that they didn't expect any results until the kids had been taking it for 6 weeks. Other studies have gone 3 months or more. Patience is required.



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20 Oct 2007, 7:39 am

There's a comprehensive review of interventions at www.researchautism.net .(Part of Bristol University) Not ".COM" as I wrote in a different post


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21 Oct 2007, 8:07 pm

They reduce most behavior of any kind (by messing with the link from thought to action). And I mean any kind (and anything a person does, at all, is behavior, I'm not just talking about odd or "bad" behavior). Unless they're causing akathisia or something. But that doesn't make them good (in fact in a population prone to movement disorders that can make them extraordinarily bad).

As far as homeopathy goes, "homeopathic" remedies don't even contain any of the contents they say they do, they're so far diluted there isn't even anything there of the "remedy" they supposedly contain. They're really expensive water. I wouldn't bother with that.

Keep in mind our repetitive behaviors, when not just tics or something, are usually there for a reason, and acting like they just need to be suppressed without even knowing the reason isn't the best way to go about anything.


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