I'm left handed, and it's kind of annoying.
Not only do typical things cater to right handed people, even some GAMES do. Popular titles such as Oblivion and Fallout 3 use a right hand dominate control style, and have no options to change it (lazy programmers). If I owned these games for the X-Box 360, I would have modded my controller itself to play them how I want to.
What is the statistic? 1 in 10 are left handed? I don't think it's hereditary either. My mother and her husband are both left handed, which is kind of odd to me. None of the people I've met are left handed, and yet the most left handed people I know personally are my mother and her husband.
I've read that left handed people are typically better than right handed people at using their non-dominant hand for more tasks. I can't relate at this moment with that though.