I dislike it. I usually keep to using Autist in German. Or Asperger-Autist.
I prefer the lack of a similar noun in English.
It's hard to believe people say 'aspie' in everyday situations to mean people who're affected by the disorder Asperger's Syndrome, a high functioning form of autism. 'aspie' doesn't sound like that to me.
I like how 'autie' sounds. To my ears, it sounds just right as an affectionate term.
Maybe I think so differently about 'aspie' because 'aspie' is often used in a non-affectionate way in a serious discussions.
If it's used in personal conversations or as an affectionate term, I consider it quite cute. Okay to use. Good even, if you're talking to kids.
But it's really irritating to me to have a serious conversation, a talk in front of an audience, a debate over the effect AS (usually) has and then someone comes along and says 'aspie' to mean a person who has AS.
That somehow destroys the whole idea of that AS can be a serious, life-long disability if someone giving an informative talk about this PDD suddenly talks of 'aspies'.
I mean, I don't hear as many people calling others 'psychos' when they talk about psychopaths or about 'schizos' when they're having a serious medical debate about schizophrenia.
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Autism + ADHD
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The trouble with having an open mind, of course, is that people will insist on coming along and trying to put things in it. Terry Pratchett