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Apera
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08 Dec 2010, 8:33 pm

http://psychcentral.com/news/2010/12/07 ... 21396.html

Personally, I think that they are making an error by only observing deficits.

Quote:
Mitochondrial dysfunction is also linked to several other neurological conditions, such as Alzheimer’s disease, Parkinson’s disease, schizophrenia and bipolar disorder.

“Children with mitochondrial diseases may present exercise intolerance, seizures and cognitive decline, among other conditions. Some will manifest disease symptoms and some will appear as sporadic cases,” said Cecilia Giulivi, professor in the Department of Molecular Biosciences in the School of Veterinary Medicine at UC Davis and the study’s lead author.

“Many of these characteristics are shared by children with autism.”


Que?


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08 Dec 2010, 8:46 pm

Makes a lot of sense to me.


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08 Dec 2010, 11:02 pm

This makes a lot of sense. Could also explain why there's so much variance in autism/asperger's cases in terms of severity. Mitochondria could exhibit varying degrees of dysfunction, giving the brain varying levels of reduced energy.



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09 Dec 2010, 12:00 am

I don't have exercise intolerance, seizures or cognitive decline. I've never heard of the former being associated with autism at all, actually.



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09 Dec 2010, 1:27 am

Well, if true, that's an as-yet-untried avenue for biomed, and moreover it actually makes sense and explains contradictory observations.

The proof is in the pudding. I think I'll use myself as a guinea pig. If I have such deficiencies, supplements should be of benefit. When I get around to it (I have mixed feelings on the idea of trying a cocktail of OTC drugs on myself, plus I don't exercise much in the winter so I couldn't judge whether my stamina increased), I'll post the results here.

I do not have seizures. I do not know how I would determine whether or not I had either of the others. I do know that I've never been particularly athletic, and have in fact been laughably horrible at physical activity my whole life.

Ideally, I would do a big study on this. Hmm. Actually, that sounds really interesting.


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Apera
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10 Dec 2010, 11:39 pm

I was talking to someone whose sin died from a severe version of this. During the discussion, I remmbered the neurologist (on the spectrum) who was redoing old scan experiments, and found that HFA typically had a greater number of base processor neurons, but lacked proper inter-connectivity between regions in the brain. I remembered an article I read in Science News that involved stimulating a rat's whiskers during a stroke, which increased blood flow to the affected region of the rat's brain which kept it functioning. Perhaps the purpose of stimming?


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