New study finds no link between measles vaccine and autism

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Chibi_Neko
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04 Sep 2008, 9:41 am

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New research further debunks any link between measles vaccine and autism, work that comes as the United States is experiencing a surge in measles cases fuelled by children left unvaccinated.

Years of research with the measles, mumps and rubella vaccine, better known as MMR, have concluded that it doesn't cause autism.

Still, some parents' fears persist, in part because of one 1998 British study that linked the vaccine with a subgroup of autistic children who also have serious gastrointestinal problems. That study reported that measles virus was lingering in the children's bowels.

Only now have researchers rigorously retested that finding, taking samples of youngsters' intestines to hunt for signs of virus with the most modern genetic technology. There is no evidence that MMR plays any role, the international team — which included researchers who first raised the issue — reported Wednesday.

"Although in fact there was evidence that this vaccine was safe in the bulk of the population, it had not been previously assessed with respect to kids with autism and GI complaints," said Dr. W. Ian Lipkin of Columbia University College of Physicians and Surgeons, who led the work published in PLoS One, the online journal of the Public Library of Science.

"We are confident there is no link between MMR and autism," Lipkin said.

Added co-author Dr. Larry Pickering of the Centers for Disease Control and Prevention: "I feel very certain that it is a safe vaccine."

Measles, a highly infectious virus best known for its red skin rash, once routinely sickened thousands of children a year and killed hundreds, until childhood vaccinations made it a rarity in this country.

But so far this year, the U.S. has counted 131 measles cases, the most in a decade. Most patients were unvaccinated. Some were infants too young for their first MMR shot, but nearly half involved children whose parents rejected vaccination, the CDC reported last month.

No one knows just how many autism patients also suffer gastrointestinal disorders, pain that they may not be able to communicate. But Lipkin said that by some estimates, up to a quarter may be affected.

The MMR fear was that the vaccine's weakened measles virus somehow lodged in and inflamed intestines, allowing waste products to escape and reach the central nervous system, Lipkin said. So his team had two questions: Does measles virus really persist in children with both disorders and not other youngsters? And did vaccination precede the GI complaints which in turn preceded autism?

Researchers studied 25 children with both autism and GI disorders, and another 13 children with the same GI disorders but no neurologic problems. The youngsters — the average age was five — all were undergoing colonoscopies for their GI conditions anyway, allowing tissue samples to be tested for genetic traces of measles virus. All had been vaccinated at younger ages.

The tests uncovered traces of measles genetic material in the bowels of one boy with autism — and one boy without autism. That doesn't prove virus never temporarily lodged in more children, but it contradicts the earlier study that raised concern.

Nor was there a relationship with vaccine timing: Just five of the 25 autistic children had MMR precede GI complaints that in turn preceded autism symptoms.

Researchers consulted some prominent vaccine critics in designing the study. California advocate Rick Rollens praised the work but said it didn't eliminate other vaccine concerns that deserve similar study. Meanwhile, he said it should draw much-needed attention to the suffering of patients like his son, who has both autism and GI disorders.

"No longer can mainstream medicine ignore the parents' claims of significant GI distress," he said.


Maybe now paranoid parents will get their act together.


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Paguk
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04 Sep 2008, 9:51 am

:( (sigh). Unlikely...short of having some nasty pandemic rear it's head, I believe that no matter how much research surfaces, it will simply not get the adequate attention needed to become common knowledge. The vaccine paranoia will likely persist as "fact" such as the "fact" that 15th century Europeans honestly thought that the world was flat and that Columbus proved them wrong or that Barak Obama is Muslim.



tomamil
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04 Sep 2008, 10:10 am

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California advocate Rick Rollens praised the work but said it didn't eliminate other vaccine concerns that deserve similar study.

this is stupid, is there any reason at all to think that a vaccine can rewire your brain and cause this neurological condition? i just cannot understand where the idea comes from. specially when it is far more likely to be genetic.

btw, in my country it is a crime if parents neglect to vaccinate their children...


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Last edited by tomamil on 04 Sep 2008, 10:31 am, edited 1 time in total.

ghouna
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04 Sep 2008, 10:15 am

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in my country it is a crime if parents neglect to vaccine their children

which country?

As a mum of two, when it was time for the MMR jab, i was asking myself so many question.
If you dont give the MMR, you are a bad mum, because those illness can be very dangerous sometimes, and you will feel guilty if your children catch one and die, or because sterile...

If you do give the MMR, you are a bad mum, people start to obeserve your kids to see if they are "normal" or not... and if anything wrong happen, then you will feel guilty...

We cannot win!!

But at the end, i decided to give my kids the MMR.


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tomamil
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04 Sep 2008, 10:28 am

ghouna wrote:
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in my country it is a crime if parents neglect to vaccinate their children

which country?

Slovakia, I know that the same is in Czech Republic too. and I believe more European countries have it.
it's called 'regular obligatory vaccination', and it includes more things than just MMR.


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Last edited by tomamil on 04 Sep 2008, 10:34 am, edited 1 time in total.

ghouna
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04 Sep 2008, 10:34 am

MERCI!


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tomamil
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04 Sep 2008, 10:39 am

ghouna wrote:
MERCI!


pas de quoi :D


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Last edited by tomamil on 04 Sep 2008, 10:39 am, edited 1 time in total.

ghouna
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04 Sep 2008, 10:39 am

tomamil wrote:
ghouna wrote:
MERCI!


pas de quoi :D


si si j insiste! ;)


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Trigger11
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04 Sep 2008, 11:44 am

I was just about to start a thread on this after reading it on Boston.com.

WASHINGTON - New research further debunks any link between measles vaccine and autism, work that comes as the nation is experiencing a surge in measles cases fueled by children left unvaccinated.

Years of research with the measles, mumps, and rubella vaccine, better known as MMR, have concluded that it doesn't cause autism. Still, some parents' fears persist, in part because of one 1998 British study that linked the vaccine with a subgroup of autistic children who also have serious gastrointestinal problems. That study reported that measles virus was lingering in the children's bowels.

Only now have researchers rigorously retested that finding, taking samples of youngsters' intestines to hunt for signs of virus with the most modern genetic technology. There is no evidence that MMR plays any role, the international team - which included researchers who first raised the issue - reported yesterday.

"Although in fact there was evidence that this vaccine was safe in the bulk of the population, it had not been previously assessed with respect to kids with autism and GI complaints," said Dr. W. Ian Lipkin of Columbia University College of Physicians and Surgeons, who led the work published in PLoS One, the online journal of the Public Library of Science.

"We are confident there is no link between MMR and autism," Lipkin said.

Added co-author Dr. Larry Pickering of the Centers for Disease Control and Prevention: "I feel very certain that it is a safe vaccine."

Measles, a highly infectious virus best known for its red skin rash, once routinely sickened thousands of children a year and killed hundreds, until childhood vaccinations made it a rarity in this country. But so far this year, the United States has counted 131 measles cases, the most in a decade. Most patients were unvaccinated. Some were infants too young for their first MMR shot, but nearly half involved children whose parents rejected vaccination, the CDC reported last month.

No one knows just how many autism patients also suffer gastrointestinal disorders, pain that they may not be able to communicate.

The MMR fear was that the vaccine's weakened measles virus somehow lodged in and inflamed intestines, allowing waste products to escape and reach the central nervous system, Lipkin said. So his team had two questions: Does measles virus really persist in children with both disorders and not other youngsters? And did vaccination precede the GI complaints which in turn preceded autism?

Researchers studied 25 children with both autism and GI disorders, and another 13 children with the same GI disorders but no neurologic problems.

The tests uncovered traces of measles genetic material in the bowels of one boy with autism - and one boy without autism.

That doesn't prove that the virus never temporarily lodged in more children, but it contradicts the earlier study that raised concern.

Nor was there a relationship with vaccine timing: Just five of the 25 autistic children had MMR precede GI complaints that in turn preceded autism symptoms.


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04 Sep 2008, 12:42 pm

Its great that this NON link has been proven, but I bet there are still those nutters who are going to exploit mothers into not having their kids jabbed. I had the MMR when I was 4 because there wasn't a vaccine before that and I can tell you that I was autistic way before then! Do these parents realise that the risk of severe brain damage and even death from the measles is WAY more common than this supposed risk!


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04 Sep 2008, 12:43 pm

I'd say maybe there's a chance people will leave this topic alone now, and finally admit the idea has no merit. Unfortunately, they've had plenty of other chances to see reason, so this probably won't make any difference at all.


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Chibi_Neko
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04 Sep 2008, 1:58 pm

Jellybean wrote:
Its great that this NON link has been proven,


What do you mean? 'source' is the link, you just need to click on it.


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Jellybean
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04 Sep 2008, 2:12 pm

I apologize, but I don't quite understand what you mean by 'source'. Maybe you misinterpreted my writing. I always get it wrong!


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04 Sep 2008, 2:26 pm

Chibi_Neko wrote:
Jellybean wrote:
Its great that this NON link has been proven,


What do you mean? 'source' is the link, you just need to click on it.


I think he means the false autism-vaccines link.


What more does that Rollens guy want? I don't get where this extreme hostility towards vaccines by some people (hippyish Westerners and Muslim fanatics, essentially) comes from. What, exactly, is so 'evil' about them? You'd think something that can prevent all sorts of awful diseases like tetanus, polio and rabies, and that eradicated smallpox, would be more popular...


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Chibi_Neko
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04 Sep 2008, 2:52 pm

pbcoll wrote:
Chibi_Neko wrote:
Jellybean wrote:
Its great that this NON link has been proven,


What do you mean? 'source' is the link, you just need to click on it.


I think he means the false autism-vaccines link.



Now I get it :oops:


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WillThePerson
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06 Sep 2008, 2:45 pm

I find it scary that they had to do a study to find this out.
Any one with common sense would know this already.