Zoloft

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I've been on Zoloft since September 2015 and have not gone up in clothing size!

Bad, bad drug. Stay away from it.

I am currently on Zoloft and have never gained weight on it (I have taken it before in the past).

Been taking it for about a year and made me gain weight. That's what I feared too and zoloft was supposed to have less probability of making you fat unlike Paxil. If it does make you fat you can always talk to your psychiatrist about switching drugs, I plan to switch medication soon.

that's what I understand about an antidepressant working, that everyone's biochem is just a little different, including how the drug is processed in the body, etc, etc

So, zoloft might work great for one person, not do much for another. But this second person might be helped by another antidepressant, even one in the same "class." And can take 4 to 8 weeks to tell, maybe more. So, in conclusion, the important thing is to stay a little loosey-goosey and be willing to move laterally.

Also it's often important to phase down in steps, even if the medicine doesn't seem to be working, just that your body may have gotten used to it.